癌症不仅与身体上的苦难有关，还与心理上的苦难有关。特别值得注意的是，身体形象失调与癌症相关的变化密切相关，这种变化常常持续到从癌症康复后。需要开发可伸缩和低门槛的干预措施，可以与面对面的癌症幸存者心理疗法结合使用。本研究的目的是调查智能手机应用的身体干预对改善癌症患者情绪的效果是否优于智能手机应用的童话故事干预（对照干预）。我们在两家瑞士医院招募了癌症患者，并进行了为期5周的每周6次的全自动智能手机干预，与每周面对面的团体身体心理疗法相结合。我们采用了一个受试者内部设计，随机将患者每天分配到身体干预或童话故事干预组。每种干预类型每周呈现3次。针对此次二次分析，使用3级混合模型估计了情绪的变化，通过3个多维情绪问卷子量表，包括好坏情绪、清醒度和平静度进行评估。此外，还调查了通过可视模拟量表评估的存在感、活力和负担的效果。根据36名参与者进行的732次干预的数据，智能手机干预后好坏情绪得到改善（β=.27; 95% CI 0.062-0.483），参与者变得更加平静（β=.98; 95% CI 0.740-1.211）。清醒度从干预前到干预后没有显著变化（β=.17; 95% CI -0.081 to 0.412）。这对于两种干预类型都成立。干预类型与好坏情绪的变化（β=-.01; 95% CI -0.439 to 0.417）、平静度的变化（β=.22; 95% CI -0.228 to 0.728）或清醒度的变化（β=.14; 95% CI -0.354 to 0.644）之间没有交互作用效应。存在感（β=.34; 95% CI 0.271-0.417）和活力（β=.35; 95% CI 0.268-0.426）从干预前到干预后增加，而负担感降低（β=-0.40; 95% CI -0.481 to 0.311）。同样，这些效果适用于两种干预类型。干预类型与存在感的干预前后变化（β=.14; 95% CI -0.104 to 0.384）、活力体验的干预前后变化（β=.06; 95% CI -0.152 to 0.265）和负担体验的干预前后变化（β=-.16; 95% CI -0.358 to 0.017）之间没有显著的交互作用效应。我们的结果表明，基于智能手机的音频引导的身体干预和童话故事都有改善癌症幸存者情绪的潜力。ClinicalTrials.gov编号NCT03707548；https://clinicaltrials.gov/study/NCT03707548.RR2-10.1186/s40359-019-0357-1。©Gunther Meinlschmidt, Astrid Grossert, Cornelia Meffert, Noa Roemmel, Viviane Hess, Christoph Rochlitz, Miklos Pless, Sabina Hunziker, Brigitta Wössmer, Ulfried Geuter, Rainer Schaefert. 原文发表于JMIR Cancer（https://cancer.jmir.org）， 2023年8月28日。

Cancer is related to not only physical but also mental suffering. Notably, body image disturbances are highly relevant to cancer-related changes often persisting beyond recovery from cancer. Scalable and low-barrier interventions that can be blended with face-to-face psychotherapy for cancer survivors are highly warranted.The aim of the study is to investigate whether smartphone-based bodily interventions are more effective to improve the mood of patients with cancer than smartphone-based fairy tale interventions (control intervention).We recruited patients with cancer in 2 Swiss hospitals and conducted daily, fully automated smartphone-based interventions 6 times a week for 5 consecutive weeks, blended with weekly face-to-face group body psychotherapy. We applied 2 types of smartphone-based interventions using a within-subject design, randomly assigning patients daily to either bodily interventions or fairy tales. Each intervention type was presented 3 times a week. For this secondary analysis, 3-level mixed models were estimated with mood assessed by the 3 Multidimensional Mood Questionnaire subscales for good-bad mood, wakefulness, and calmness as key indicators. In addition, the effects on experience of presence, vitality, and burden assessed with visual analog scales were investigated.Based on the data from s=732 interventions performed by 36 participants, good-bad mood improved (β=.27; 95% CI 0.062-0.483), and participants became calmer (β=.98; 95% CI 0.740-1.211) following smartphone-based interventions. Wakefulness did not significantly change from pre- to postsmartphone-based intervention (β=.17; 95% CI -0.081 to 0.412). This was true for both intervention types. There was no interaction effect of intervention type with change in good-bad mood (β=-.01; 95% CI -0.439 to 0.417), calmness (β=.22; 95% CI -0.228 to 0.728), or wakefulness (β=.14; 95% CI -0.354 to 0.644). Experience of presence (β=.34; 95% CI 0.271-0.417) and vitality (β=.35; 95% CI 0.268-0.426) increased from pre- to postsmartphone-based intervention, while experience of burden decreased (β=-0.40; 95% CI -0.481 to 0.311). Again, these effects were present for both intervention types. There were no significant interaction effects of intervention type with pre- to postintervention changes in experience of presence (β=.14; 95% CI -0.104 to 0.384), experience of vitality (β=.06; 95% CI -0.152 to 0.265), and experience of burden (β=-.16; 95% CI -0.358 to 0.017).Our results suggest that both smartphone-based audio-guided bodily interventions and fairy tales have the potential to improve the mood of cancer survivors.ClinicalTrials.gov NCT03707548; https://clinicaltrials.gov/study/NCT03707548.RR2-10.1186/s40359-019-0357-1.©Gunther Meinlschmidt, Astrid Grossert, Cornelia Meffert, Noa Roemmel, Viviane Hess, Christoph Rochlitz, Miklos Pless, Sabina Hunziker, Brigitta Wössmer, Ulfried Geuter, Rainer Schaefert. Originally published in JMIR Cancer (https://cancer.jmir.org), 28.08.2023.