传统甲状腺切除术在颈部前方留下明显的疤痕。通过内窥镜的甲状腺切除术可能会实现更好的美容效果，并在术后改善生活质量。本研究旨在对大量接受无气体内窥镜甲状腺切除（GET）经前胸壁途径（ACA）的患者进行完整的回顾，包括长期随访期，并评估该程序的结果和局限性。研究中包括了从2003年到2022年在我院接受GET经ACA的1413例患者。总结并分析了人口学、临床病理特征、肿瘤学和美容结果。手术指征为686（48.5%）患者的乳头状甲状腺癌和727（51.5%）患者的良性甲状腺疾病。其中，802（56.8%）例患者接受半甲状腺切除术，611（43.2%）例患者接受亚全/全甲状腺切除术。同时，598（42.3%）例进行颈中部淋巴结清扫术，88（6.2%）例进行颈侧淋巴结清扫术。最常见的并发症是短暂性低副甲状腺功能，发生率为2.9%。在2至232个月的随访期内，有3例患者确认局部复发。大多数患者对美容效果感到满意。无气体内窥镜甲状腺切除术通过前胸壁途径是一种安全可行的程序，可实现出色的肿瘤学和美容结果。© 2023. 作者及 exclusively licence to Springer Science+Business Media, LLC, part of Springer Nature.

Conventional thyroidectomy leaves an eye-catching scar in the anterior neck region. Endoscopic thyroidectomy may achieve a better esthetic effect and improve quality of life postoperatively. The aim of this study was to undertake a complete review of a large cohort of the patients undergoing gasless endoscopic thyroidectomy (GET) via anterior chest approach (ACA) with a long-term follow-up period, and evaluate the results and limits of this procedure.Between 2003 and 2022, 1413 patients undergoing GET via ACA in our department were included. The demographic, clinicopathological characteristics, oncologic and esthetic outcomes were summarized and analyzed.The indication for surgery was papillary thyroid carcinoma in 686 (48.5%) patients and benign thyroid diseases in 727 (51.5%) patients. Among them, 802 (56.8%) patients took hemithyroidectomy, and 611 (43.2%) patients did sub-total/total thyroidectomy. Meanwhile, 598 (42.3%) ones had central neck dissection, while 88 (6.2%) lateral neck dissection. The most common complication was transient hypoparathyroidism with an incidence of 2.9%. During the follow-up period of 2 to 232 months, three patients were confirmed locoregional recurrence. Most of the patients were satisfied with the cosmetic results.Gasless endoscopic thyroidectomy via anterior chest approach is a safe and feasible procedure, which could achieve excellent oncologic and esthetic outcomes.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.