艾滋病和癌症标本资源（ACSR）的目标是通过免费提供丰富注释的生物标本和数据来推动艾滋病/艾滋病相关癌症研究和治疗的进展。ACSR获取、储存并平等分发这些样本和相关临床数据给进行艾滋病/艾滋病相关研究的调查人员，全球范围内适格的研究人员都可以免费使用。目前，ACSR是全球支持研究艾滋病相关恶性肿瘤的适格研究人员使用的唯一人类生物标本生物库。本综述介绍了ACSR的历史和组织结构，以及其存货中的标本类型和标本请求的流程。此外，综述还总结了在过去5年中在ACSR的支持下进行的研究的概述，并提供了对HIV感染者肿瘤发展的重要新发现的综述，包括艾滋病相关和非艾滋病相关的恶性疾病。© 2023. BioMed Central Ltd., Springer Nature部分所有。

The goal of the AIDS and Cancer Specimen Resource (ACSR) is to play a major role in the advancement of HIV/AIDS cancer-related research/treatment by providing richly annotated biospecimens and data to researchers at no cost. The ACSR acquires, stores, and equitably distributes these samples and associated clinical data to investigators conducting HIV/AIDS-related research, at no costs. Currently, it is the only biorepository of human biospecimens from people with HIV and cancer available to eligible researchers globally who are studying HIV associated malignancies.This review describes the history and organizational structure of the ACSR, its types of specimens in its inventory, and the process of requesting specimens. In addition, the review provides an overview of research that was performed over the last 5 years with its support and gives a summary of important new findings acquired by this research into the development of cancers in people with HIV, including both Aids-related and non-Aids-related malignancies.© 2023. BioMed Central Ltd., part of Springer Nature.