多中心网状组织细胞增生症：一种罕见且具有致残性的疾病。
Multicentric Reticulohistiocytosis-A rare and disabling disease.
发表日期：2023 Sep
作者：
Omowunmi Ashaolu, Selwyn Ng, Shaun Smale, Jenny Hughes
来源：
Arthritis & Rheumatology
摘要：
多中心纤维组织细胞增生症是一种罕见的多系统性疾病，与丘疹结节性皮肤病变、严重关节炎和恶性肿瘤相关。组织病理学显示组织细胞含有丰富的嗜酸性玻璃样质地的细胞质和多核巨细胞。早期识别、年龄适宜的恶性肿瘤检查以及治疗对于防止日常生活活动受损非常重要。© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age-appropriate malignancy work-up and treatment is important to prevent impairment of daily life activity.© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.