来自真菌的代谢物和生物活性化合物的新视角。
A New Perspective on Metabolites and Bioactive Compounds from Fungi.
发表日期:2023 Aug 30
作者:
Thananjeyan Balasubramaniyam, Seo-Ree Choi, Vinod Kumar Nathan, Abhishikta Basu, Joon-Hwa Lee
来源:
Food & Function
摘要:
真菌在解决重要全球问题中发挥着重要的作用。利用基于真菌的过程和产品可以通过充分利用自然资源来促进可持续发展。由于真菌具有非凡的有机化合物生成能力,它们与其他生物体有所不同。它们对全球人们的心理和生理福祉是必不可少的。它们是优秀的维生素、色素、水解酶、生物燃料、有机酸、多糖和抗生素、抗癌治疗、降低胆固醇药物和免疫抑制剂等次生代谢产物的生产者。其中还包括生物燃料。此外,它们还产生多糖。我们提供了对于次生代谢产物在制药业、食品业、纺织业和交通运输业等各个行业中的重要性的简明阐释。除了提供对生物合成调控和基因工程可能性的更好理解之外,改进的实验室流程可用于选择无致毒真菌菌株,从而使安全商业产品的生产量变得更大。真菌在工业环境中的重要性是本综述的研究主题。
Fungi play an important role in the solution to important global problems. Making use of processes and goods that are based on fungi can help promote sustainability by making the most efficient use of natural resources. Fungi stand apart from other organisms due to their extraordinary capacity to generate organic compounds. They are necessary for the psychological and physiological well-being of people worldwide. They are excellent producers of vitamins, pigments, hydrolytic enzymes, biofuels, organic acids, polysaccharides, and secondary metabolites such as antibiotics, anticancer treatments, hypocholesterolemic pharmaceuticals, and immunosuppressants. Other secondary metabolites include biofuels. In addition, polysaccharides are produced by them. We provide a condensed explanation of the significance of secondary metabolites in a variety of industries, such as the pharmaceutical industry, the food industry, the textile industry, and the transportation industry. In addition to providing a better understanding of biosynthetic regulation and the possibilities of genetic engineering, improved laboratory processes for the selection of nontoxigenic fungal strains have permitted the manufacture of larger quantities of safe commercial items. The significance of fungi in industrial settings is the topic that will be investigated in this review.