机器人辅助根治性前列腺切除术后高危前列腺癌的尿控功能
Urinary continence in high-risk prostate cancer after robot-assisted radical prostatectomy.
发表日期:2023 Aug 31
作者:
Xiaobo Wu, Chris Ho-Ming Wong, Giorgio Gandaglia, Peter Ka-Fung Chiu,
来源:
Disease Models & Mechanisms
摘要:
尿失禁是前列腺癌(PCa)患者进行机器人辅助根治性前列腺切除术(RARP)后常见的术后并发症。尽管RARP在高危PCa(HRPC)治疗中的应用越来越广泛,但人们对该亚组中报道的尿控恢复结果的充分性仍然存在关切。本综述旨在阐明HRPC患者在RARP术后尿控恢复方面的状态。从RARP术后6到24个月,HRPC的尿控恢复率报告的低于中/低风险组。预测模型显示年龄、肥胖、种族、疾病状态和手术方法是尿控恢复的预测因子。神经安全技术和Retzius节约术也在高危情况下减少尿失禁方面起到一定作用。与其他风险组相比,HRPC患者的RARP术似乎与尿控恶化相关。对RARP术后尿失禁的预测和预防需要多模态途径。进一步的研究是必要的,以提高HRPC患者在接受RARP术后的尿控恢复结果。版权所有©2023 Wolters Kluwer Health,Inc.保留所有权利。
Urinary incontinence is common postoperative complication following robot-assisted radical prostatectomy (RARP) in patients with prostate cancer (PCa). Despite the increasing adoption of RARP in the treatment of high-risk PCa (HRPC), concerns persist regarding the adequacy of reported continence outcomes in this subgroup. This review aims to illuminate the state of continence recovery in HRPC patients post-RARP.Urinary continence (UC) recovery rates in HRPC was reported to be lower than the intermediate/low-risk counterparts from 6 to 24 months post-RARP. Predictive models showed that age, obesity, race, disease status, and surgical approaches represent predictors of continence recovery. Special techniques like NeuroSAFE technique and Retzius-Sparing approach also play a role in reducing incontinence also in the high-risk scenario.RARP for HRPC appears to be associated with worse continence compared with other risk groups. A multimodality approach for prediction and prevention of incontinence after RARP is vital. Further research into this area is necessary to enhance continence recovery outcomes in HRPC patients undergoing RARP.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.