基于Blatter单元并由乙炔和烯烃间隔连接的双自由基已经合成。所有分子均显示出较大的双自由基特性和较低的单重态-三重态能隙。通过稳态和时间分辨吸收光谱对其最低能级激发态的光物理性质进行了详细研究。我们充分确定了主要的吸收带和最低能级激发态的发射完全缺失。此外，还进行了计算研究，帮助确定了最低能级激发态与基态之间的锥形交叉，产生了对吸收的辐射高效的光热转换。此外，我们还确认了接近80%的突出光热转换效率，接近双自由基领域的最高水平。首次使用稳定的双自由基在近红外区域应用于肿瘤细胞的光热疗法，具有良好的稳定性和令人满意的性能。© 2023 Wiley-VCH GmbH.

Diradicals based on the Blatter units and connected by acetylene and alkene spacers have been prepared. All the molecules show sizably large diradical character and low energy singlet-triplet energy gaps. Their photo-physical properties concerning their lowest energy excited state have been studied in detail by steady-state and time-resolved absorption spectroscopy. We have fully identified the main optical absorption band and full absence of emission from the lowest energy excited state. A computational study has been also carried out that has helped to identify the presence of a conical intersection between the lowest energy excited state and the ground state which produces a highly efficient light-to-heat conversion of the absorbed radiation. Furthermore, an outstanding photo-thermal conversion near 80% has been confirmed, close to the highest in the diradicaloid field. For the first time, stable diradicals are applied to photo-thermal therapy of tumor cells with good stability and satisfactory performance at near-infrared region.© 2023 Wiley-VCH GmbH.