从老挝采样的植物Garcinia gracilis中分离出了35个多种多样的多酚，属于七个结构类。用光谱学、X射线衍射以及实验和计算的电子圆二色谱(ECD)方法确定了九个新化合物的结构，分别是gargarcilones A-I (1-3, 5-7, 10, 12和17)。另外，我们修正了cochinchinoxanthone和cochinchinoxanthone C的立体化学赋值。我们评估了这些化合物对五种人类肿瘤细胞系（HL-60、A549、SMMC-7721、MDA-MB-231和SW480）的抗增殖活性。化合物1-4、7和8表现出细胞毒性活性，IC50值为0.5-8.9 μM。化合物3在SMMC-7721细胞中显著诱导细胞凋亡。

Thirty-five diverse polyphenols, belonging to seven structure classes, were isolated from Garcinia gracilis, a medicinal and edible plant sampled from Laos. The structures of nine new compounds, gargarcilones A-I (1-3, 5-7, 10, 12, and 17), were established using spectroscopic, X-ray diffraction, and experimental and calculated ECD methods. Additionally, we revised the stereochemical assignment of cochinchinoxanthone and cochinchinoxanthone C. The compounds were evaluated for antiproliferative activity against five human tumor cell lines (HL-60, A549, SMMC-7721, MDA-MB-231, and SW480). Compounds 1-4, 7, and 8 exhibited cytotoxic activity with IC50 values of 0.5-8.9 μM. Compound 3 significantly induced apoptosis in SMMC-7721 cells.