研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

具有肝肺综合征的患者存在经叶内动静脉侧支与穿孔血管双侧分流并发生多发脑卒中。

Bilateral Arteriovenous Shunting Through Pial and Perforating Vessels With Multiple Strokes in a Patient With Hepatopulmonary Syndrome.

发表日期:2023 Jul
作者: Baha Aljeradat, Manisha Koneru, Renato Oliveira, Hamza Shaikh
来源: DIABETES & METABOLISM

摘要:

肝肺综合征(Hepatopulmonary syndrome,HPS)是一种以慢性肝病、肺内动静脉分流和肺泡-动脉氧分压梯度增加为特征的疾病。本病例报告介绍了一名54岁男性患者,患有中风、肝硬化、门静脉血栓形成、高血压、糖尿病和膀胱癌,近5年头痛和混乱症状逐渐加重。数字减影血管造影(DSA)显示多发双侧动静脉分流,提示存在与HPS类似的分流机制。我们提议,这个独特的病例可能为了解HPS的病理生理与脑部弥漫性动静脉分流以及两种病例中缺血和出血事件增加的风险之间的相似之处提供有价值的洞见。进一步的研究需要建立对肝病患者这种关系的更清晰的理解以及其对患者的影响。版权所有 © 2023, Aljeradat等人。
Hepatopulmonary syndrome (HPS) is a condition characterized by chronic liver disease, intrapulmonary arteriovenous shunting, and increased alveolar-arterial oxygen gradient. This case report presents a 54-year-old male patient with a history of stroke, liver cirrhosis, portal vein thrombosis, hypertension, diabetes, and bladder cancer, who presented with worsening headaches and confusion over the course of five years. Digital subtraction angiogram (DSA) revealed multiple bilateral arteriovenous shunts, suggesting a shunting mechanism similar to that observed in HPS. We propose that this unique case could provide valuable insights into the parallels between the pathophysiology of HPS and diffuse arteriovenous shunting in the brain and the increased risk of ischemic and hemorrhagic events in both cases. Further studies are needed to establish a clearer understanding of this relationship and its implications for patients with chronic liver disease.Copyright © 2023, Aljeradat et al.