食管疾病，包括胃食管反流病（GERD）、嗜酸性食管炎（EoE）和食管癌，可能会受到气候变化的影响。我们的综述描述了气候变化对与食管疾病相关的危险因素的影响，并推测这些与气候相关的因素如何影响食管疾病及其治疗。气候变化导致极端天气条件（降雨变化、洪水、干旱和森林火灾）和全球变暖。这些后果影响了人类对水和食物的基本需求，导致人口动态变化，并对消化健康带来重大威胁，包括常见的食管疾病如GERD、EoE和食管癌。食管疾病在气候变化下的变化模式可能是通过营养、污染物、微塑料和微生物群-肠道-脑轴等危险因素介导的。医疗过程本身，包括常用于食管疾病诊断和治疗的胃肠内镜方法，可能反过来通过废弃塑料和温室气体排放向气候变化做出贡献，从而形成气候变化生命周期。打破这个周期需要在个体层面、社区层面和国家政策层面进行变革。预防是关键，个体需识别和纠正危险因素，并减少碳足迹。ABC（倡导、广播、合作）活动有助于提高社区层面的意识。更高层次的项目，如应对气候影响的强化（BRACE），将带来公共卫生适应策略在国家层面的更广泛和更大规模的采用。气候变化对食管疾病的影响很可能是真实的，并通过多种危险因素创造了一个气候变化生命周期，只有在个体、社区和国家层面进行变革才能打破这一模式。 © 2023. 本文作者（们）在Springer Science+Business Media, LLC的独家许可下发表，Springer Nature的一部分。

Esophageal disorders, including gastroesophageal reflux disease (GERD), eosinophilic esophagitis (EoE), and esophageal cancer, may be affected by climate change. Our review describes the impact of climate change on risk factors associated with esophageal diseases and speculates how these climate-related factors impacted esophageal disorders and their management.Climate change is responsible for extreme weather conditions (shifts in rainfall, floods, droughts, and forest fires) and global warming. These consequences affect basic human needs of water and food, causing changes in population dynamics and pose significant threats to digestive health, including common esophageal disorders like GERD, EoE, and esophageal cancers. The changing patterns of esophageal diseases with climate change are likely mediated through risk factors, including nutrition, pollutants, microplastics, and the microbiota-gut-brain axis. The healthcare process itself, including GI endoscopy practices commonly employed in diagnosing and therapeutics of esophageal diseases, may, in turn, contribute to climate change through plastic wastage and greenhouse gas emissions, thus creating the climate change lifecycle. Breaking the cycle would involve changes at the individual level, community level, and national policy level. Prevention is key, with individuals identifying and remediating risk factors and reducing carbon footprints. The ABC (Advocacy, Broadcast, and Collaborate) activities would help enhance awareness at the community level. Higher-level programs such as the Bracing Resilience Against Climate Effects (BRACE) would lead to broader and larger-scale adoption of public health adaptation strategies at the national level. The impact of climate change on esophageal disorders is likely real, mediated by several risk factors, and creates a climate change lifecycle that may only break if changes are made at individual, community, and national levels.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.