在亚洲，有一些国家已经在合作临床试验方面建立了长期而成功的国家儿童癌症研究团队，但许多国家仍然没有这样的团队。建立国家儿童癌症研究团队的过程充满了许多障碍，这些障碍在不同国家之间各不相同。临床试验运营的基本要求之一是拥有一个能够让大多数患有癌症的儿童接受所提供治疗的经得起承受的医疗保健体系。亚洲国家儿童癌症患儿的医疗保险覆盖率在不同国家之间从不到20%不等，甚至高达100%，与此同时，临床试验的操作也必须相应地进行调整。研究人员的短缺是很常见的，包括医生、护士、研究协调员和数据管理人员。亚洲儿科血液学与肿瘤学协作组的成立旨在为亚洲国家推动国际临床试验提供良好的平台。

In Asia, a few countries have a long and established history of collaborative clinical trials successfully formed national children's cancer study groups, but many still do not have such groups. The process of forming national children's cancer groups is fraught with many hurdles, which varies among the countries. One of the basic requirements for running clinical trials is an affordable health care system in which most of the children with cancer can receive the proposed treatment. The health insurance coverage for children with cancer varies from <20% to as high as 100% among Asian countries, and the operation of clinical trials must also be adjusted accordingly. Shortage of research personnel is common, including medical, nursing, research coordinators, and data managers. The establishment of the Asian Pediatric Hematology and Oncology Group aims to provide a good platform for promotion of international clinical trials in the Asian countries.