本研究旨在利用文献计量学方法对原发性甲状旁腺功能亢进（PHPT）的科学文章进行描述性分析。通过分析学术成果中各个研究组成部分（作者、期刊、机构、国家）之间的联系，旨在总结PHPT的智力结构，确定最近的研究趋势和全球生产力。我们从Web of Science数据库中提取了1980年至2022年间发表的3954篇PHPT文章，并采用文献计量学方法进行了分析。我们使用文献计量学网络可视化图来识别热门话题、引文分析和国际合作。我们使用斯皮尔曼相关系数进行相关性分析。最具生产力的3位作者是Bilezikian JP.（n = 87）、Silverberg SJ.（n = 72）和Akerstrom G.（n = 57）。最具生产力的3个机构是哥伦比亚大学（n = 133）、法国研究大学（n = 127）和乌普萨拉大学（n = 98）。最具生产力的3个期刊是《Surgery》（n = 216）、《Journal of Clinical Endocrinology and Metabolism》（n = 201）和《World Journal of Surgery》（n = 148）。对PHPT文献做出最大贡献的3个国家是美利坚合众国（n = 1062，占总数的26.8%）、意大利（n = 346，占总数的8.7%）和英国（n = 274，占总数的6.9%）。从过去到现在，最研究的主题有甲状旁腺切除术、高钙血症、甲状旁腺激素/腺瘤/腺体、钙/钙调节剂、显像学/西斯他米、骨密度、超声、维生素D、骨质疏松症、微创甲状旁腺手术、棕色瘤、肾钙化/肾结石、多发性内分泌腺瘤1型、正钙血症、妊娠、影像学/术前影像学、甲状旁腺癌/癌瘤、无症状原发性甲状旁腺功能亢进以及西娜卡塞。最近几年的热门话题包括正钙血症性原发性甲状旁腺功能亢进、骨小梁得分、儿童、CDC73、微波消融、射频消融、右善-单克隆抗体治疗、西娜卡塞、术前影像学、影像学、诊断、CT、PET、PET/CT、4D/CT、SPECT/CT、F-18-氟代脱氧膦胆碱、生活质量、骨折和代谢综合征。我们可以预测，未来几年PHPT的研究趋势将会增长。除了美国和欧洲国家这类具有大型经济实力的西方国家外，日本和土耳其也被认为是PHPT文献发展的领先国家。本研究为对PHPT感兴趣的临床医生和其他研究人员提供了有关PHPT的智力结构和全球生产力的重要信息。版权所有 © 2023 作者。由 Wolters Kluwer Health, Inc. 发表。

The aim of this study was to perform a descriptive analysis of scientific articles about primary hyperparathyroidism (PHPT) using bibliometric approaches. By analyzing the links between the various research components (authors, journals, institutions, countries) of the academic outputs, it was aimed to summarize the intellectual structure of PHPT, identify recent research trends, and determine the global productivity. Three thousand nine hundred fifty-four articles on PHPT published between 1980 and 2022 were pulled from the Web of Science database and analyzed using bibliometric approaches. Bibliometric network visualization maps were used to identify trending topics, citation analysis, and international collaborations. Spearman correlation coefficient was used for correlation analysis. The 3 most prolific authors are Bilezikian JP. (n = 87), Silverberg SJ. (n = 72) and Akerstrom G. (n = 57). The top 3 most productive institutions were Columbia University (n = 133), Udice French Research Universities (n = 127) and Uppsala University (n = 98). The top 3 most productive journals were Surgery (n = 216), Journal of Clinical Endocrinology and Metabolism (n = 201) and World Journal of Surgery (n = 148). The top 3 contributing countries to the PHPT literature were United States of America (n = 1062, 26.8%), Italy (346, 8.7%) and United Kingdom (274, 6.9%). The most studied topics from past to present are parathyroidectomy, hypercalcemia, parathyroid hormone/adenoma/glands, calcium/calcimimetics, scintigraphy/sestamibi, bone mineral density, ultrasound, vitamin D, osteoporosis, minimally invasive parathyroidectomy, brown tumor, nephrocalcinosis/nephrolithiasis, multiple endocrine neoplasia type 1, normocalcemia, pregnancy, imaging/preoperative imaging, parathyroid cancer/carcinoma, asymptomatic primary hyperparathyroidism, and cinacalcet. The trending topics in recent years were normocalcemic primary hyperparathyroidism, trabecular bone score, children, CDC73, microwave ablation, radiofrequency ablation, denosumab, cinacalcet, preoperative imaging, imaging, diagnosis, CT, PET, PET/CT, 4D/CT, SPECT/CT, F-18-fluorocholine, quality of life, fractures, and metabolic syndrome. We can say that there will be an increasing research trend on PHPT in the coming years. In addition to the Western countries such as the United States and European countries with large economies, Japan and Turkey were also identified as leading countries in the development of the PHPT literature. This study provides significant information about the intellectual structure and global productivity of PHPT to clinicians and other researchers interested on PHPT.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.