泪腺源性眶腺样囊性癌（adenoid cystic carcinoma，ACC）是一种非常罕见的上皮性肿瘤，通常起源于泪腺。与此同时，目前的治疗选择非常有限，如放射治疗和化疗。我们报告了一例患者使用安罗替尼联合放射治疗的治疗情况。一个13岁的女孩最初因“左眼肿胀半年以上，在左眶泪腺样囊性癌手术12天后”。最初出现在左眼外侧上眼睑的肿胀，逐渐扩大并偶有疼痛。眶泪腺样囊性癌。诊断为眶ACC后，她接受了左侧眶肿块切除术，并接受了33次的辅助放射治疗，但后来出现了脑转移。她拒绝进一步治疗，在疾病再次进展后接受了25次放射治疗和安罗替尼治疗。现在患者已随访8个月，但未发现进展。基于此，我们假设放射治疗联合安罗替尼对ACC或ACC转移有效。版权所有 © 2023 作者。 Wolters Kluwer Health, Inc. 发表。

Adenoid cystic carcinoma (ACC) of orbit is a very rare epithelial tumor, often originating from the lacrimal glands. At the same time, treatment options are currently limited, such as radiation, chemotherapy. We report a case of a patient treated with antirotinib combined with radiotherapy.A 13-year-old girl was initially admitted with "left eye swelling for over half a year, 12 days after surgery for left orbital adenoid cystic carcinoma". Initial swelling of the lateral upper eyelid of the left eye, with gradual enlargement and occasional pain.Left orbital adenoid cystic carcinoma.After diagnosis of orbital ACC, she underwent resection of the left orbital mass, and received 33 times of adjuvant radiotherapy, but brain metastases appeared later. She refused further treatment, and received 25 times of radiotherapy and anlotinib therapy after the disease progressed again.Now the patient has been followed up for 8 months, but no progress was found.Based on this, we hypothesized that radiation therapy in combination with anlotinib is effective for ACC or ACC metastases.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.