神经内分泌颈部癌（NECC）罕见。NECC患者教育资源有限，导致许多人通过患者主导的社交网络寻求信息。我们旨在研究NECC患者焦虑和抑郁水平与社交媒体使用之间的关系。在我们的NECC登记册中，我们发放了七份关于社交媒体使用、焦虑和抑郁的调查问卷给活着的NECC患者。主要结果是Social Network Time Use Scale（SONTUS）总分与广泛性焦虑障碍量表（GAD-7）和流行病学中心抑郁量表（CESD）总分之间的关联。共有88名患者参与登记；81名完成至少1份调查问卷的患者被纳入分析。完成SONTUS问卷的患者中，97%（70/72）是低至中等社交媒体使用者。72名患者中，74%（53/72）在过去4周内访问过由患者主导的NECC支持团体的Facebook页面，并且其中的79%（42/53）表示获得了有用的信息。在未访问该页面的患者中，47%（9/19）报告该页面引发了焦虑和/或悲伤。整个队列的GAD-7和CESD平均得分分别为7.3和18.1。社交媒体使用与这些得分之间的Spearman相关系数是显著的（GAD-7：0.23 [p = 0.05]；CESD：0.25 [p = 0.04]）。随着SONTUS总分的增加，中度/重度焦虑和抑郁的概率比率分别为1.26（95％CI 1.03-1.55；p = 0.03）和1.23（95％CI 1.01-1.49；p = 0.04）。NECC患者表现出低至中等的社交媒体使用率和相对较高的焦虑和抑郁水平。社交媒体使用的增加与焦虑和抑郁水平的升高相关。© 2023年Elsevier Inc.版权所有。

Neuroendocrine cervical carcinoma (NECC) is rare. Educational resources are limited for NECC patients, leading many to seek information online through patient-led social networks. We sought to characterize the relationships between anxiety and depression levels and social media use among NECC patients.Seven surveys assessing social media use, anxiety, and depression were distributed to living NECC patients enrolled in our NECC registry. The primary outcomes were associations between Social Network Time Use Scale (SONTUS) global score and Generalized Anxiety Disorder (GAD-7) and Center for Epidemiologic Studies Depression Scale (CESD) total scores.Eighty-eight patients enrolled; 81 who completed at least 1 survey were included. Ninety-seven percent (70/72) of patients completing SONTUS were low-to-average social media users. Seventy-four percent (53/72) of patients visited a patient-led NECC support-group page on Facebook within the past 4 weeks, and of those, 79% (42/53) reported receiving useful information. Among the patients who did not visit the page, 47% (9/19) reported that the page elicited anxiety and/or sadness. The mean GAD-7 and CES-D scores for the entire cohort were 7.3 and 18.1, respectively. The Spearman correlations between social media use and these scores were significant (GAD-7: 0.23 [p = 0.05]; CESD: 0.25 [p = 0.04]). The estimated odds ratios for moderate/severe anxiety and depression as a function of SONTUS global score were 1.26 (95% CI 1.03-1.55; p = 0.03) and 1.23 (95% CI 1.01-1.49; p = 0.04), respectively.NECC patients demonstrated low-to-average social media use and relatively high anxiety and depression. Increased social media use was associated with elevated anxiety and depression.Copyright © 2023 Elsevier Inc. All rights reserved.