研究动态
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膳食质量指数与乳腺癌风险:一项病例对照研究。

Dietary quality index and the risk of breast cancer: a case-control study.

发表日期:2023 Sep 01
作者: Fatemeh Pourhabibi-Zarandi, Masoud Amini Kahrizsangi, Sevda Eskandarzadeh, Fatemeh Mansouri, Mohebat Vali, Saba Jalali, Zeinab Heidari, Zainab Shateri, Mehran Nouri, Bahram Rashidkhani
来源: Food & Function

摘要:

食物质量是乳腺癌(BrCa)病因的重要决定因素,但需要进一步研究来探讨这种关系。因此,我们尝试评估使用国际饮食质量指数(DQI-I)评估的饮食质量与伊朗人群中的BrCa之间的关系。在本次病例对照研究中,选择了134名最近被诊断为BrCa的女性和267名未患BrCa的女性作为病例组和对照组。使用食物频率问卷的个体食物摄入数据计算DQI-I。此外,我们利用多变量 logistic 回归模型评估了 DQI-I 与 BrCa 的关联。 我们发现在经过充分调整的模型中,DQI-I 的最后一个三分位与 BrCa 的几率之间存在显著关联(悠率比(OR)=0.30;95%置信区间(CI):0.15-0.56)。基于绝经状态的亚组分析还显示出绝经前和绝经后妇女BrCa几率的显著降低(绝经前:OR=0.27;95%CI:0.10-0.70,绝经后:OR=0.35;95%CI:0.13-0.92)。 我们的发现表明,更高的 DQI-I 分数与较低的 BrCa 几率相关。根据我们的研究,健康的饮食模式对于BrCa的预防至关重要。 © 2023. BioMed Central Ltd.,施普林格自然出版集团的一部分。
Diet quality is a significant determinant in the etiology of breast cancer (BrCa), but further studies are required to explore this relationship. Therefore, we tried to assess if diet quality, assessed using the Diet Quality Index-International (DQI-I), was related to BrCa among the Iranian population.In the present case-control research, 134 women with a recent diagnosis of BrCa and 267 without BrCa were selected as case and control groups. Individual food intake data from a food frequency questionnaire was used to compute DQI-I. Also, the multivariable logistic regression models were utilized to evaluate the association between DQI-I and BrCa odds .We found a significant association between the last tertile of DQI-I and BrCa odds in the fully adjusted model (odds ratio (OR) = 0.30; 95% confidence interval (CI): 0.15-0.56). The subgroup analysis based on menopausal status also showed a significant decrease in BrCa odds in pre-and post-menopausal women (pre-menopausal: OR = 0.27; 95% CI: 0.10-0.70 - post-menopausal status: OR = 0.35; 95% CI: 0.13-0.92).Our findings indicated that a higher DQI-I score was related to a lower chance of BrCa. According to our research, a healthy diet pattern is crucial for BrCa prevention.© 2023. BioMed Central Ltd., part of Springer Nature.