蜂蜜是通过花蜜和蜜蜂的上呼吸道消化道的自然食品副产物，被认为是最受人们认可的天然食品之一。关于蜂蜜的药用重要性的意义在世界上最古老的医学文献中有充分的记录。然而，当前的城市化、环境污染以及农业和养蜂业的变化已经导致了蜂蜜中各种不同类型的污染。其中，农药污染已成为全球性的主要问题之一。本综述主要关注蜂蜜中农药残留物的发生情况的最新进展，以及长期暴露于污染农药残留物的蜂蜜对人体生理功能的影响，可能导致各种癌症的发展。我们的研究结果表明，农业和养蜂业中对农药的不受限制使用导致了蜂蜜中农药残留物的发生。因此，定期食用这种蜂蜜将对人类健康构成严重威胁，因为其中大多数农药已被报告为潜在的致癌物。本综述将引起蜂蜜消费者、科学界、养蜂农民以及管理机构对花卉栽培、农业以及其他相关实践中农药使用的严格监控的关注。版权所有 © 2023 Elsevier Ltd. 发表。

Honey is the most recognized natural food by-product of flower nectar and the upper aero-digestive tract of the honeybees. Significance of honey for its medicinal importance are well-documented in the world's oldest medical literatures. However, the current urbanization, environmental contaminations and changes in agricultural, as well as apiculture practices has led to various types of contaminations in honey. Among all, pesticide contamination has become one of the major issues worldwide. This review focuses on the recent updates concerning pesticides occurrence in honey, as well as how the repeated use and long-term exposure to honey contaminated with pesticide residues could affect the human physiological functions, possibly leading to the development of various cancers. Our findings suggests that uncontrolled use of pesticides in farming and apiculture practices leads to the occurrence of pesticides residues in honey. Therefore, regular consumption of such honey will pose a serious threat to human health, since most of the pesticides has been reported as potential carcinogens. This review will draw the attention of honey consumers, scientific communities, apiculture farmers, as well as governing bodies to strictly monitor the pesticide usage in floriculture, agriculture as well as other related practices.Copyright © 2023. Published by Elsevier Ltd.