研究动态
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强汉江口道虫感染的流行病学和控制:对胆管癌预防的意义。

Epidemiology and Control of Opisthorchis viverrini Infection: Implications for Cholangiocarcinoma Prevention.

发表日期:2023
作者: Narong Khuntikeo, Bandit Thinkhamrop, Thomas Crellen, Chatanun Eamudomkarn, Trevor N Petney, Ross H Andrews, Paiboon Sithithaworn
来源: Parasites & Vectors

摘要:

众所周知,华蟲是胆管癌(CCA)发展的最重要危险因素,因此也被称为致癌寄生虫。有效控制和消除华蟲感染应显著减少与华蟲相关的胆管癌。本章介绍了三种最近开发的创新工具的详细信息,即伊散队列数据库软件、华蟲快速诊断试纸和超声波通信系统。过去和现在的控制项目,即教育,药物治疗和卫生设施已被讨论,并强调了需要一个全面的控制项目,包括初级、中级和终末患者护理项目以确认和管理疑似胆管癌病例。也简要描述了数学模型方法控制华蟲和胆管癌。此外,我们强调了泰国在控制华蟲和胆管癌方面的目前进展,以及拓展到东南亚邻国的潜力。© 2023。作者(们),在独家许可下授予Springer Nature Switzerland AG。
It is known that Opisthorchis viverrini (OV) is the most significant risk factor for the development of cholangiocarcinoma (CCA); hence, it is also known as carcinogenic parasite. Effective control and elimination of OV infection should significantly reduce O. viverrini-related CCA. This chapter includes details of the three recently developed innovative tools, namely the Isan cohort database software, an OV-RDT for screening of O. viverrini, and an ultrasound telecommunication system. Past and current control programs, i.e., education, medication, and sanitation were discussed and stressed the need for a comprehensive control program which encompasses primary, secondary, and tertiary patient care programs for confirmation and management of suspected CCA cases. The approach of mathematical modeling for control of OV and CCA was also briefly described. Additionally, we highlighted the current progress toward control of OV and CCA in Thailand and potential for expansion into nearby countries in Southeast Asia.© 2023. The Author(s), under exclusive license to Springer Nature Switzerland AG.