作为生物学和医学领域的科学家，你精通英语和简体中文。请将以下段落准确地翻译成简化的中文，符合学术论文的语言模式，并保持原陈述的结构： 作为生物体的必需微量元素，铁对于维持生物体的健康至关重要。过量的铁可以促进活性氧自由基（ROS）的积累，从而损害细胞和组织。铁过载和脂质过氧化是一种与自噬、凋亡和坏死不同、被认为是新型的程序性细胞死亡形式的特征，越来越多的研究聚焦于铁死亡。最近的证据表明，铁死亡与女性生殖系统疾病（FRDs）的发展有关，包括多囊卵巢综合征（PCOS）、早期卵巢功能不全（POI）、子宫内膜异位症（EMs）、卵巢癌（OC）、子痫前期（PE）和自然流产（SA）。与铁死亡相关联的途径和基因可能参与调节颗粒细胞增殖和分泌、卵母细胞发育、卵巢储备功能、早期胚胎发育和胎盘氧化应激的过程。然而，其确切机制尚未完全揭示。因此，我们的综述从系统的角度阐述了铁死亡的发生机制及其在FRDs发展中的研究进展，旨在为临床靶向铁死亡相关途径和调控因子管理FRDs提供文献参考。 版权所有©2023该作者。由Elsevier Masson SAS出版。保留所有权利。

Iron, as an essential trace element for the organism, is vital for maintaining the organism's health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus damaging cells and tissues. Ferroptosis is a novel form of programmed cell death distinguished by iron overload and lipid peroxidation, which is unique from autophagy, apoptosis and necrosis, more and more studies are focusing on ferroptosis. Recent evidence suggests that ferroptosis is associated with the development of female reproductive disorders (FRDs), including polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI), endometriosis (EMs), ovarian cancer (OC), preeclampsia (PE) and spontaneous abortion (SA). Pathways and genes associated with ferroptosis may participate in processes that regulate granulosa cell proliferation and secretion, oocyte development, ovarian reserve function, early embryonic development and placental oxidative stress. However, its exact mechanism has not been fully revealed. Therefore, our review systematically elaborates the occurrence mechanism of ferroptosis and its research progress in the development of FRDs, with a view to providing literature references for clinical targeting of ferroptosis -related pathways and regulatory factors for the management of FRDs.Copyright © 2023 The Authors. Published by Elsevier Masson SAS.. All rights reserved.