本研究旨在比较评估术中失血量（IBL）和围手术期并发症在术前栓塞（PE）和非栓塞（NE）联合脊柱肿瘤手术之间的差异，确定适合PE的脊柱肿瘤手术亚组。两名评审人员对PubMed和EMBASE进行系统搜索，并通过检索的研究参考文献进行额外搜索。平均IBL和围手术期并发症率被用作一般定量综合研究中的效应值，通过直接计算来进行数值合成。使用标准化均数差异（SMD）和加权均数差异（WMD）来进行IBL的荟萃分析，使用并发症的比值比（OR）来进行荟萃分析。使用I2统计量评估异质性。评审人员选择了17篇已发表的研究进行一般定量综合和荟萃分析。NE组脊柱肿瘤手术的平均IBL为1786.3 mL，而PE组为1716.4 mL。两组之间的平均IBL相似。脊柱肿瘤手术IBL的汇总WMD和SMD分别为324.15 mL（95% CI 89.50-1640.9, p = 0.007）和0.398（95% CI 0.114-0.682, p = 0.006）。与NE组相比，PE组的主要并发症和主要出血性并发症发病率分别减少了7.80%和5.71%。PE组与NE组相比，PE相关并发症的风险仅增加了1.53%。脊柱肿瘤手术主要并发症的荟萃OR为1.426（95% CI 0.760-2.674；p = 0.269）。PE可能适用于脊柱肿瘤手术及其一些亚组。从并发症的角度来看，PE也可能是脊柱肿瘤手术的可行选择。© 2023. 作者，独家授权给Springer-Verlag GmbH Germany，属于Springer Nature的一部分。

The present study aimed to comparatively evaluate intraoperative blood loss (IBL) and perioperative complications between preoperative embolization (PE) and nonembolization (NE) combined with spinal tumor surgeries as well as to determine the subgroup of spinal tumor surgeries suitable for PE.A systematic search in PubMed and EMBASE and an additional search by reference lists of the retrieved studies were undertaken by two reviewers. The mean IBL and perioperative complication rate were employed as the effect size in the general quantitative synthesis through direct calculation. Meta-analysis was performed using standardized mean difference (SMD) and weighted mean difference (WMD) of IBL and the odds ratio (OR) of complications. Heterogeneity was assessed using the I2 statistic.The reviewers selected 17 published studies for the general quantitative synthesis and meta-analyses. The mean IBL of spinal tumor surgeries was 1786.3 mL in the NE group and 1716.4 mL in the PE group. The mean IBL between the two groups was similar. The pooled WMD and SMD of IBL in spinal tumor surgeries was 324.15 mL (95% CI 89.50-1640.9, p = 0.007) and 0.398 (95% CI 0.114-0.682, p = 0.006), respectively. The reduction of the PE group compared with the NE group for the rates of major complications and major hemorrhagic complications were 7.80% and 5.71%, respectively. The risk of PE-related complications in the PE group was only 1.53% more than in the PE group. The pooled OR of major complications in spinal tumor surgeries was 1.426 (95% CI 0.760-2.674; p = 0.269).PE may be suitable for spinal tumor surgeries and some subgroups. From the perspective of complications, PE may also be a feasible option for spinal tumor surgeries.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.