生物组织的死亡类型因温度的不同而异，主要分为凋亡和坏死。基于这一基础，正在研究一种新的治疗方法，称为光热疗法。光热疗法是一种基于光热效应的治疗技术，其优势在于无需切口，因此无出血。本研究对鳞状细胞癌的光热疗法进行了数值分析。所采用的光热药剂为金纳米颗粒，通过改变激光照射瘤组织的角度来确认光热疗法效果。基于三个凋亡相关的变量，定量评估了光热疗法的效果。此外，还研究了在不同激光照射角度下，达到最佳治疗效果所需的瘤组织中金纳米颗粒的体积分数和激光强度。因此，本研究的发现有助于未来光热疗法的实际应用。

The type of death of biological tissue varies with temperature and is broadly classified as apoptosis and necrosis. A new treatment called photothermal therapy is being studied on this basis. Photothermal therapy is a treatment technique based on photothermal effects and has the advantage of not requiring incisions and, therefore, no bleeding. In this study, a numerical analysis of photothermal therapy for squamous cell carcinoma was performed. Photothermal agents used were gold nanoparticles, and the photothermal therapy effect was confirmed by changing the angle of the laser irradiating the tumor tissue. The effectiveness of photothermal therapy was quantitatively assessed on the basis of three apoptotic variables. Further, the volume fraction of gold nanoparticles in the tumor tissue and laser intensity with optimal therapeutic effect for different laser irradiation angles were studied. Thus, the findings of this study can aid the practical implementation of photothermal therapy in the future.