目的 本横断面观察研究旨在确定在印度泰米尔纳德邦科伯托尔市G. Kuppuswamy Naidu纪念医院治疗期间，癌症患者的焦虑和抑郁的患病率，以及焦虑和抑郁与年龄、性别、婚姻状况、教育程度、职业、经济支持、治疗时间、疾病类型和恶性程度等各种因素的相关性，使用医院焦虑和抑郁量表（HADS）。方法 共纳入162名接受不同癌症治疗（化疗/手术/综合治疗）的患者，所有患者都接受了HADS评估。使用卡方检验研究了焦虑分数与年龄、部位和性别等各种因素之间的关联。结果 39名（24.1%）患者患有严重焦虑，60名（37%）患者患有边缘性焦虑，63名（38.9%）患者被确定为正常。53名（32.7%）患者患有严重抑郁，47名（29%）患者患有边缘性抑郁，62名（38.3%）患者被确定为正常。本研究发现，教育程度和职业状况是导致癌症患者焦虑和抑郁患病率增加的显著因素（p < 0.05）。本研究还发现，乳腺和胃肠癌患者的抑郁患病率较其他癌症类型高。结论 本研究针对泰米尔纳德邦的癌症患者焦虑和抑郁患病率进行了贡献。虽然研究人群较小，这是本研究的局限性，但它提供了一个概述，即教育程度和职业状况对焦虑和抑郁产生重要影响，这方面的研究过去很少。为了有效管理这一问题，应让患者了解来自各慈善团体、政府政策和保险的经济支持，以便他们能够改善生活质量并更有信心地管理临床情况。这些发现呼吁在癌症护理中进行早期的精神干预，通过关注改善患者的心理稳定和服药依从性，提高患者的生活质量，从而获得癌症治疗的积极结果。版权所有© 2023，Radhakrishnan等人。

Objective This cross-sectional, observational study aimed at finding the prevalence of anxiety and depression in cancer patients and the correlation of anxiety and depression with various factors, such as age, sex, marital status, educational status, occupation, financial support, duration, type of care, sort of carcinoma, and stages of malignancy, among cancer patients attending the G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, Tamil Nadu, India from July 2022 to December 2022, using the Hospital Anxiety and Depression Scale (HADS). Methods A total of 162 cancer patients referred for various cancer therapies (chemo/surgery/combination therapies) were included. All patients were administered the HADS. The association between anxiety scores and various factors such as age, site, and sex was found using the chi-square test. Results Thirty-nine (24.1%) patients had severe anxiety, 60 (37%) patients had borderline anxiety, and 63 (38.9%) patients were found to be normal. Fifty-three (32.7%) patients had severe depression, 47 (29%) patients had borderline depression, and 62 (38.3%) patients were found to be normal. The findings of this study indicate that educational status and occupational status are the significant factors (p < 0.05) responsible for increasing the risk of prevalence of anxiety and depression in cancer patients. Another interesting observation in this study was that patients with breast and gastrointestinal cancer had the highest prevalence of depression among other cancer types. Conclusions The present study contributed to the prevalence of anxiety and depression in cancer patients in Tamil Nadu, India. While the study population is small, which is a limitation of the present study, it has provided an overview that educational status and occupation contribute significantly to anxiety and depression, which has not been explored much in the past. To efficiently manage this, patients should be made aware of the financial support available from various philanthropic groups, government policies, and insurance so that they can improve their quality of life and manage their clinical condition in a more confident manner. These findings call for the need for early psychiatric interventions in cancer care to improve the quality of life of patients by focusing on improving patients' mental stability and adherence to the medications for providing positive outcomes from the cancer treatments.Copyright © 2023, Radhakrishnan et al.