为了替代超声波测厚，我们研究了脉冲放射治疗后经线性加速器（LINAC）进行的低剂量立体定向光子放射治疗后的脉络膜黑色素瘤特征与无进展生存期（PFS）是否有关。在一组回溯性数据集中，我们使用线性混合模型评估了PFS与肿瘤特征之间的关联，尤其是厚度、最大基底直径（LBD）、基底面积和体积。结果显示厚度和LBD与PFS显著相关。在16例因黑色素瘤复发或进展而行眼摘除手术的患者亚组中，在手术前均值的厚度和LBD发生了显著变化。均值PFS为42 ± 30个月。针对治疗后的脉络膜黑色素瘤监测，可能不需要超声波测厚，我们建议在未来使用眼底照相来进行连续LBD评估。©2023. 作者著作权归属。

In an effort to replace ultrasonography-based thickness measurements, we investigated whether choroidal melanoma characteristics are related to progression-free survival (PFS) in patients monitored after linear accelerator (LINAC)-based hypofractionated stereotactic photon radiotherapy.In a retrospective dataset, we used a linear mixed model to assess the associations between PFS and tumor characteristics; in particular, thickness, largest basal diameter (LBD), base area and volume.Thickness and LBD are statistically significantly associated with PFS. In a subgroup of 16 patients undergoing enucleation due to melanoma recurrence or progression, there were statistically significant changes in mean thickness and LBD before surgery. Mean PFS was 42 ± 30 months.Ultrasonography-based thickness measurements may not be necessary for treated choroidal melanoma monitoring; instead, we propose sequential LBD assessments, which should preferably be performed using fundus photography in future.© 2023. The Author(s).