为了评估 COVID-19 疫情对骨科住院人数和非 COVID-19 患者骨科保健结果的影响，选取了来自六个不同国家的七家医院。采用多中心中断时间序列（ITS）分析方法。这些医院是在全球卫生数据@工作合作项目中协作的。选取了 COVID-19 疫情前（2018年1月至2020年2月）和疫情期间（2020年3月至2021年6月）的非 COVID-19 骨科患者作为研究对象。住院人数被分为以下几类：（1）急性住院（下肢骨折/股骨颈骨折/恶性骨折/关节脱位/上肢骨折）；（2）亚急性住院（骨癌）；（3）选择性住院（骨关节炎）。根据病例组合计算出院内死亡率、长期（最高十分位数）住院时间和住院再度入院率的实际观察值与预期比值（O/E ratio）。预期比值基于病例组合计算出来。采用 ITS 设计来评估 COVID-19 疫情与疫情前期间每月 O/E 比值的水平变化和/或趋势变化。在研究中纳入了 69,221 名非 COVID-19 骨科患者（疫情前期）和 22,940 名非 COVID-19 骨科患者（COVID-19 疫情期间）。所有住院类别的住院人数在 COVID-19 疫情期间均有所减少（范围：33%-45%），同时较复杂的患者有所增加，即有较高百分比的患者患有 ≥1 种合并症（53.8% vs 49.8%，p<0.001）。对于大多数诊断组的患者，COVID-19 疫情与患者保健结果没有显著变化。只有对于诊断为恶性骨折的患者（疫情前期 n=1671，疫情期间 n=749）和下肢骨折患者（疫情前期 n=9898，疫情期间 n=3307），COVID-19 疫情与即时死亡率显著减少（水平变化为-77.7%，95% CI -127.9% 至 -25.7%）以及再入院率趋势显著下降（每月趋势变化为-6.3%，95% CI -11.0% 至 -1.6%）相关。在 COVID-19 疫情期间，全球参与医院的急性、亚急性和选择性骨科住院人数均有所减少，而大多数非 COVID-19 骨科患者的总体保健结果与 COVID-19 患者激增所引起的压力相比保持不变。© 2023 作者（或其雇主）。根据 CC BY-NC 可以授权再使用。无商业再使用。请参阅权利和许可。由 BMJ 发布。

To assess across seven hospitals from six different countries the extent to which the COVID-19 pandemic affected the volumes of orthopaedic hospital admissions and patient outcomes for non-COVID-19 patients admitted for orthopaedic care.A multi-centre interrupted time series (ITS) analysis.Seven hospitals from six countries who collaborated within the Global Health Data@Work collaborative.Non-COVID-19 patients admitted for orthopaedic care during the pre-pandemic (January/2018-February/2020) and COVID-19 pandemic (March/2020-June/2021) period. Admissions were categorised as: (1) acute admissions (lower limb fractures/neck of femur fractures/pathological fractures/joint dislocations/upper limb fractures); (2) subacute admissions (bone cancer); (3) elective admissions (osteoarthritis).Monthly observed versus expected ratios (O/E) were calculated for in-hospital mortality, long (upper-decile) length-of-stay and hospital readmissions, with expected rates calculated based on case-mix. An ITS design was used to estimate the change in level and/or trend of the monthly O/E ratio by comparing the COVID-19 pandemic with the pre-pandemic period.69 221 (pre-pandemic) and 22 940 (COVID-19 pandemic) non-COVID-19 orthopaedic patient admissions were included. Admission volumes were reduced during the COVID-19 pandemic for all admission categories (range: 33%-45%), with more complex patients treated as shown by higher percentages of patients admitted with ≥1 comorbidity (53.8% versus 49.8%, p<0.001). The COVID-19 pandemic was not associated with significant changes in patient outcomes for most diagnostic groups. Only for patients diagnosed with pathological fractures (pre-pandemic n=1671 and pandemic n=749), the COVID-19 pandemic was significantly associated with an immediate mortality reduction (level change of -77.7%, 95% CI -127.9% to -25.7%) and for lower limb fracture patients (pre-pandemic n=9898 and pandemic n=3307) with a significantly reduced trend in readmissions (trend change of -6.3% per month, 95% CI -11.0% to -1.6%).Acute, subacute, as well as elective orthopaedic hospital admissions volumes were reduced in all global participating hospitals during the COVID-19 pandemic, while overall patient outcomes for most admitted non-COVID-19 patients remained the same despite the strain caused by the surge of COVID-19 patients.© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.