癌症免疫逃避中的细胞外囊泡脂质。
Extracellular vesicle lipids in cancer immunoevasion.
发表日期：2023 Sep 02
作者：
Siyu Chen, Dalila Iannotta, Megan L O'Mara, Jenifer Pendiuk Goncalves, Joy Wolfram
来源：
Trends in Cancer
摘要：
最近的研究揭示了癌细胞产生的细胞外囊泡（EV）对免疫反应具有调节作用。脂质具有多样的生物学功能，并被认为促进肿瘤的恶性化。然而，EV脂质在癌症进展中的免疫逃避作用尚不清楚。然而，对癌细胞产生的EV脂质的研究对诊断和治疗干预有很大的潜力。版权所有 © 2023 Elsevier Inc. 保留所有权利。
Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.Copyright © 2023 Elsevier Inc. All rights reserved.