无论是后天受伤还是先天畸形，都经常会导致儿童终身残疾，并对认知能力产生重大影响。远程计算机化认知训练（CCT）可以在生态环境中推进康复连续性。本随机对照临床试验（RCT）评估了一个8周的多领域在家CCT对非进展性后天脑损伤（ABI）、脑肿瘤（BT）和先天性脑畸形（CBM）患者（年龄11-16岁）样本的疗效。根据步进楔形研究设计，患者被随机分为两组：首先训练组，在基线评估后立即开始CCT，和首先等待组，在与训练相当时间的时间后开始CCT（8周）。进行了训练后和长期（6个月后）的变化评估。研究结果显示，两组在CCT后的视觉空间工作记忆都有所改善，并且在6个月后仍能保持改善，而在其他认知或心理测量中没有发现其他变化。这些发现表明，多领域CCT可以在视觉空间工作记忆方面产生益处，与现有文献数据一致，报告指出计算机游戏会严重涉及视觉空间能力。我们推测，在进行CCT后，通过对同一认知能力进行长时间的训练，可能会产生最大的变化。© 2023. Springer Nature Limited.

Both acquired injuries and congenital malformations often cause lifelong disabilities in children, with a significant impact on cognitive abilities. Remote computerized cognitive training (CCT) may be delivered in ecological settings to favour rehabilitation continuity. This randomized clinical trial (RCT) evaluated the efficacy of an 8-week multi-domain, home-based CCT in a sample of patients aged 11-16 years with non-progressive acquired brain injury (ABI), brain tumor (BT) and congenital brain malformation (CBM). Following a stepped-wedge research design, patients were randomized into two groups: Training-first group, which started the CCT immediately after baseline assessment and Waiting-first group, which started the CCT after a period of time comparable to that required by the training (8 weeks). Post-training and long-term (6 months) changes were assessed. Both groups improved on visual-spatial working memory after the CCT, with benefits maintained after 6 months, while no other changes in cognitive or psychological measures were found. These findings suggest that a multi-domain CCT can generate benefits in visual-spatial working memory, in accordance with data from extant literature reporting that computer games heavily engage visuo-spatial abilities. We speculate that is tapping on the same cognitive ability with a prolonged training that may generate the greatest change after a CCT.© 2023. Springer Nature Limited.