高嗜酸性综合征是一组异质性的罕见疾病，其特征为嗜酸性细胞相关器官损伤和外周血嗜酸性细胞增多。高嗜酸性综合征可能是由多种临床实体引起的，例如药物过敏反应、寄生虫感染、自身免疫性疾病和恶性肿瘤。弓形虫病是由弓形虫属幼虫引起的寄生虫感染。通常是一种儿童疾病，侵犯肝脏等器官，但也可以影响任何器官。高嗜酸性综合征和多器官受累在成人中是非常罕见的表现，尤其在弓形虫感染中更为罕见。然而，由于不同因素的影响，可能存在该病的漏诊情况，包括一些国家的实验室基础设施不足、缺乏统一的病例定义和有限的监测基础设施，估计病例数量成为一个挑战。因此，我们在此报告了一例可能的高嗜酸性综合征病例，其伴有弓形虫犬感染引起的多器官受累，患者为一名79岁的瑞士女性，有缺血性脑血管意外病史和完全切除的非小细胞支气管癌，通过阿苯达唑和类固醇成功治疗。© 作者 2023。

Hypereosinophilic syndromes are a heterogeneous group of rare diseases characterized by eosinophil-related organ damage and peripheral blood hypereosinophilia. Hypereosinophilic syndromes may occur secondary to a variety of clinical entities, for example, drug hypersensitivity reactions, parasitic infections, autoimmune disorders, and malignancies. Toxocariasis is a parasitic infection caused by the larval stage of the Toxocara species. It is usually a childhood disease and invades organs such as the liver but can affect any organ. Hypereosinophilic syndrome and multiorgan involvement are very rare manifestations of Toxocara infection, especially in adults. However, the disease may be underdiagnosed because of different factors, including a lack of laboratory infrastructure in some countries, a lack of uniform case definitions, and limited surveillance infrastructure, with its estimation constituting a challenge. We, therefore, present a probable case of hypereosinophilic syndrome with multiorgan involvement secondary to infection with Toxocara canis in a 79-year-old Swiss female patient with a medical history of ischemic cerebrovascular insult and a curatively resected non-small-cell bronchial carcinoma, successfully treated with albendazole and steroids.© The Author(s) 2023.