L-岩藻糖是一种具有广泛应用潜力的六碳糖。它具有抗肿瘤作用，可缓解肠道疾病。在食品工业中，它具有乳化剂的潜力。它还被用作功能性食品和抗衰老护肤产品的成分。然而，目前尚无法大规模制备高纯度的L-岩藻糖，其制备仍需进一步开发。本综述总结了L-岩藻糖的制备方法，包括化学合成、酶合成、微生物发酵以及从藻类中的分离和提纯。详细介绍了L-岩藻糖的检测方法，例如L-岩藻糖特异性凝集素、检测L-岩藻糖脱氢酶、半胱氨酸-硫酸法、高效液相色谱、气相色谱和生物传感器等。在本综述中，回顾了L-岩藻糖的性质和药理作用，制备方法和常用的检测方法，以作为参考资料。版权所有©2023 Elsevier Ltd. 保留所有权利。

l-fucose is a six-carbon sugar that has potential applications in many fields. It exerts antitumor effects and could relieve intestinal disease. It exhibits potential as an emulsifier in the food industry. It is also used as a functional food and in anti-aging skincare products. However, at present, it is not possible to prepare high-purity l-fucose on a large scale, and its preparation needs further development. This review summarizes the preparation methods of l-fucose including chemical synthesis, enzymatic synthesis, microbial fermentation, and separation and purification from algae. The detection methods of l-fucose are also introduced in detail, such as l-fucose-specific lectin, detection l-fucose dehydrogenase, cysteine-sulfuric acid method, high-performance liquid chromatography, gas chromatography, and biosensors. In this review, the properties and pharmacological effects of l-fucose; preparation methods, and the commonly used detection methods of l-fucose are reviewed to serve as a reference material.Copyright © 2023 Elsevier Ltd. All rights reserved.