独立纤维瘤（SFT）可发生于各种解剖位置，最常见的是四肢表浅和深层软组织，其次是腹膜后、内脏器官和骨骼。头颈部可能存在少量肿瘤，主要位于眶、鼻窦道、口腔，极少见于涎腺。涎腺中，腮腺是最常受累的部位。总体而言，涎腺中的SFT很罕见，通常为原发肿瘤。在涎腺中发生转移是非常罕见的。我们在一个31岁的年轻女性患者中展示了转移至腮腺的SFT的细胞学发现，该诊断在细胞块上借助免疫细胞化学（ICC）予以确认。制片高度细胞化，呈主要为离散的圆形至椭圆形肿瘤细胞，轻度异形性，粗糙的染色质，不明显的核仁和稀少的细胞质。观察到有丝分裂和局部坏死区域。淋巴腺体结构不存在，排除非霍奇金淋巴瘤。这些特征表明存在一种差异化差的恶性肿瘤，鉴别诊断可能为肉瘤、肌上皮癌和多形腺瘤癌样癌。进行了一组ICC，STAT6的阳性有助于得出SFT的正确诊断。© 2023 Wiley Periodicals LLC.

Solitary fibrous tumor (SFT) can occur in varied anatomic locations, most commonly being the extremities-superficial and deep soft tissues, followed by retroperitoneum, visceral organs, and the bone. Head and neck region may harbor a few with a predilection for the orbit and sinonasal tract, oral cavity, and rarely the salivary glands. The parotid gland is most involved among all salivary glands. Overall, SFT in salivary glands is rare and mostly seen as a primary tumor. The occurrence of metastasis to the parotid gland is exceedingly uncommon. We present cytological findings of SFT, metastatic to the parotid gland in a young 31-year-old lady where the diagnosis was confirmed with the help of immunocytochemistry (ICC) on the cell block. The smears were highly cellular and showed predominantly discrete round to oval tumor cells with mild pleomorphism, coarse chromatin, inconspicuous nucleoli, and scanty cytoplasm. Mitosis and focal areas of necrosis were noted. Lymphoglandular bodies were absent ruling out a non-Hodgkin lymphoma. Features were of a poorly differentiated malignant tumor with differentials being sarcoma, myoepithelial carcinoma, and carcinoma ex-pleomorphic adenoma. A panel of ICC was done and positivity for signal transducer and activator of transcription 6 (STAT6) helped in clinching the correct diagnosis of SFT.© 2023 Wiley Periodicals LLC.