质子束在肿瘤治疗中的核反应研究。
Study of Nuclear Reactions in Therapy of Tumors with Proton Beams.
发表日期：2023 Aug 29
作者：
Maxim Azarkin, Martin Kirakosyan, Vladimir Ryabov
来源：
PHYSICAL THERAPY & REHABILITATION JOURNAL
摘要：
本文利用Geant 4模拟，评估了质子放疗中人体等效材料中质子、α粒子和中子的核反应产物。在本研究中，我们还检查了Bi、Au、^11B和^10B敏化剂纳米颗粒的存在对核反应的增强情况。我们证明质子束在组织中引发了可观的核反应产物。然而，发现由于敏化剂纳米颗粒的存在，核反应产物的增强效应微不足道。
This paper presents an assessment of nuclear reaction yields of protons, α-particles, and neutrons in human tissue-equivalentmaterial in proton therapy using a simulation with Geant 4. In this study, we also check an enhancement of nuclear reactions due to the presence of Bi, Au, 11B, and 10B radiosensitizer nanoparticles. We demonstrate that a proton beam induces a noticeable amount of nuclear reactions in the tissue. Nevertheless, the enhancement of nuclear reaction products due to radiosensitizer nanoparticles is found to be negligible.