研究动态
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口腔肿瘤治疗后的吞咽问题:一项为期五年的前瞻性研究。

Swallowing after Oral Oncological Treatment: A Five-Year Prospective Study.

发表日期:2023 Sep 01
作者: Caroline M Speksnijder, Lucía Ortiz-Comino, Anton F J de Haan, Carolina Fernández-Lao, Remco de Bree, Matthias A W Merkx
来源: PHYSICAL THERAPY & REHABILITATION JOURNAL

摘要:

口腔癌术后患者的吞咽恢复仍然面临挑战。不同的因素可能会影响这些患者的吞咽功能。本研究的目的是确定与癌症治疗后5年内的吞咽功能相关的因素。测量了123例接受口腔癌治疗的患者的吞咽5毫升水和15毫升苹果酱的持续时间和频率。采用混合模型分析法确定相关因素。年龄影响了所有测量的吞咽结果。评估时间点、性别、肿瘤位置、最大舌力和舌部触觉感受功能与水和苹果酱的吞咽持续时间有关,肿瘤分类与水的吞咽时间有关,饮酒与苹果酱的吞咽时间有关。评估时间点、癌症治疗、最大舌力和舌部触觉感受功能与水和苹果酱的吞咽频率有关。诊断时年龄较大、女性以及治疗前定期饮酒的患者在癌症治疗后可能存在较差的吞咽功能。符合这些条件的患者在临床随访期间应进行吞咽评估,并在需要时接受吞咽治疗。在治疗过程中,需要重视优化舌部功能以维持最佳吞咽功能。
Swallowing rehabilitation in curative treated patients with oral cancer is still a challenge. Different factors may influence these patients' swallowing function. The aim of this study was to identify factors associated with swallowing function up to 5 years after cancer treatment.Swallowing duration and frequency of 5 mL water and 15 mL applesauce were measured in 123 patients treated for oral cancer. Mixed model analyses were performed to identify associated factors.Age influenced all measured swallowing outcomes. Assessment moment, gender, tumor location, maximum tongue force, and tactile sensory function of the tongue were associated with both water and applesauce swallowing duration, tumor classification was associated with water swallowing duration, and alcohol consumption was associated with applesauce swallowing duration. Assessment moment, cancer treatment, maximum tongue force, and tactile sensory function of the tongue were associated with water and applesauce swallowing frequency.Patients who are older at diagnosis, women, and patients who regularly consume alcohol before their treatment may have poorer swallow functioning after curative oral cancer treatment. Patients that fit these criteria should have their swallowing evaluated during clinical follow-ups and sent to swallowing therapy when needed. During this therapy, optimizing tongue function needs attention to maintain an optimal swallowing function.