皮肤癌是一种以皮肤细胞异常增长为特征的疾病，主要由于暴露于阳光或人工源如日光浴床的紫外辐射所致。不同类型的皮肤癌包括黑色素瘤、基底细胞癌和鳞状细胞癌。尽管靶向治疗方面取得了进展，但预防和治疗皮肤恶性肿瘤仍需要一种更安全、更高效的方法。香料拥有悠久的历史，可以增强食物的风味、口感和色彩，由种子、水果、树皮、根部或花朵等植物部分提取而来，是重要的烹饪成分。然而，它们的价值不仅限于烹饪领域。一些香料含有活性物质，包括酚类化合物，这些化合物以其显著的生物学效应而闻名。由于其可能在疾病预防和治疗中发挥作用，特别是对癌症，这些化合物已经引起了科研工作者的关注。本综述旨在考察香料来源的酚类化合物作为预防或治疗管理皮肤癌的潜力。通过编制和分析现有知识，本综述旨在提供见解，以指导未来研究发现新的抗癌植物化学物质，并揭示抗击皮肤癌的额外机制。

Skin cancer is a condition characterized by the abnormal growth of skin cells, primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Different types of skin cancer include melanoma, basal cell carcinoma, and squamous cell carcinoma. Despite the advancements in targeted therapies, there is still a need for a safer, highly efficient approach to preventing and treating cutaneous malignancies. Spices have a rich history dating back thousands of years and are renowned for their ability to enhance the flavor, taste, and color of food. Derived from various plant parts like seeds, fruits, bark, roots, or flowers, spices are important culinary ingredients. However, their value extends beyond the culinary realm. Some spices contain bioactive compounds, including phenolic compounds, which are known for their significant biological effects. These compounds have attracted attention in scientific research due to their potential health benefits, including their possible role in disease prevention and treatment, such as cancer. This review focuses on examining the potential of spice-derived phenolic compounds as preventive or therapeutic agents for managing skin cancers. By compiling and analyzing the available knowledge, this review aims to provide insights that can guide future research in identifying new anticancer phytochemicals and uncovering additional mechanisms for combating skin cancer.