乳碱综合征在荷兰是高钙血症罕见的原因之一，通常是由于摄入大量钙和可吸收碱而引起。一个38岁的女性患者因剧烈的腹痛、呕吐和体重减轻住院。实验室结果显示高钙血症和急性肾损伤。最初我们怀疑高钙血症可能与原发性甲状旁腺功能亢进症、具有骨转移的恶性肿瘤或肉芽肿性疾病有关。但胃十二指肠镜检查显示十二指肠溃疡，后来发现是与幽门螺杆菌相关。详尽的病史显示患者曾大量摄入牛奶和抗酸药物以缓解胃灼热症状。根据这个病史，诊断为乳碱综合征。该病例旨在强调在高钙血症患者中进行详尽的病史采集的重要性。应该在所有出现高钙血症的患者中评估非处方药物和乳制品的使用情况。

Milk-alkali syndrome is a rare cause of hypercalcemia in the Netherlands, due to ingestion of large amounts of calcium and absorbable alkali.A 38-year-old female patient was admitted with severe stomach pain, vomiting and weight loss. Laboratory results showed hypercalcemia and acute kidney injury. We initially suspected that the hypercalcemia was related to primary hyperparathyroidism, a malignancy with bone metastasis or a granulomatous disease. Gastroduodenoscopy, however, revealed a duodenal ulcer, which turned out to be Helicobacter pylori-related. A thorough history revealed that the patient had consumed large amounts of milk and antacids to relieve symptoms of heartburn. In light of this history, milk-alkali syndrome was diagnosed.The case aims to underline the importance of a thorough history in patients with hypercalcemia. The use of over-the-counter medications and dairy products should be evaluated in all patients presenting with hypercalcemia.