研究动态
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《天麻的传统用途、植物化学、药理学、应用和质量控制:一篇综述》

Traditional uses, phytochemistry, pharmacology, applications, and quality control of Gastrodia elata Blume: A comprehensive review.

发表日期:2023 Sep 07
作者: Meng-Qi Gong, Fei-Fan Lai, Jian-Zhen Chen, Xiao-Hong Li, Ya-Jie Chen, Yu He
来源: JOURNAL OF ETHNOPHARMACOLOGY

摘要:

鸢尾兰(Gastrodia elata Blume, 简称G. elata)在亚洲国家有着悠久的历史应用,其块茎、种子和茎可以用于药物、食品或保健产品。本研究旨在对G. elata在传统用途、植物化学、药理学、应用及质量控制方面的研究进展进行系统且最新的分析,为该植物的开发和利用提供科学参考。利用PubMed、Web of Science、Google Scholar、ScienceDirect、SciFinder和CNKI等电子数据库收集G. elata的相关文献。包括鸢尾兰在内的关键词与其他相关主题术语进行截断,如酚类化合物、多糖、苷类、神经保护、学习记忆改善效果、心脏保护、应用及质量控制等。据报道,该植物含有大约134种化学成分,主要归类为酚类化合物、多糖、苷类、有机酸和甾醇。此外,临床前研究表明,G. elata具有多种功能,包括神经保护、学习记忆改善效果、心脏保护、血管调节、抗抑郁、抗癌和其他效应。目前,G. elata已广泛应用于临床和食品领域。现有文献显示,G. elata的质量可能受到起源、真菌及收获时间等因素的影响,这将对药效产生影响。根据过去的研究,G. elata是一种具有多种活性成分和药理活性的潜在药用和食用植物,在医药和食品业有着高应用价值。然而,目前鲜少研究关注多糖的结构表征和非药用部分的研究,因此进一步全面研究G. elata的多糖结构和非药用部分对于充分利用鸢尾兰资源至关重要。版权所有 © 2023. 由Elsevier B.V.出版。
Gastrodia elata Blume (G. elata) has a long historical application in Asian countries and its tubers, seeds, and stalks are capable of being utilized for medicine, food, or health care products.This study aimed to offer a systematic and up-to-date analysis of the current review of the G. elata research advances in traditional uses, phytochemistry, pharmacology, applications, and quality control, as well as a scientific reference for the development and utilization of this plant.Electronic databases including PubMed, Web of Science, Google Scholar, ScienceDirect, SciFinder, and CNKI were used for the collection of publications on G. elata. The following keywords of G. elata were used truncated with other relevant topic terms, such as phenolic compounds, polysaccharides, glycosides, neuroprotection, learning and memory improvement effects, cardioprotection, applications, and quality control.s: Approximately 134 chemical components mainly categorizing as phenolic compounds, polysaccharides, glycosides, organic acids, and sterols were reported from this plant. Moreover, preclinical studies indicated that G. elata performs several functions, including neuroprotection, learning and memory improvement effects, cardioprotection, vaso-modulatory effect, anti-depression, anti-cancer, and other effects. Currently, G. elata has been widely applied to clinics and foods. The available literature shows that the quality of G. elata might be affected by factors such as origin, fungus, and harvest time, which will have an impact on the drug efficacy. According to past research, G. elata is a potential medicinal and edible plant with several active components and pharmacological activity that has a high application value in medicine and the food business. Nevertheless, few studies have concentrated on characterization of polysaccharides structure and study of non-medicinal parts, implying that further comprehensive research on its polysaccharides structure and non-medicinal parts is critical for full utilization of resources of G. elata.Copyright © 2023. Published by Elsevier B.V.