IASLC胸腺上皮肿瘤分期项目:对IASLC/ ITMIG胸腺上皮肿瘤淋巴结图谱的再评估,为即将发布的第9版TNM恶性肿瘤分类提供参考。
The IASLC Thymic Epithelial Tumors Staging Project: A Re-Assessment of the ITMIG/IASLC Lymph Node Map for Thymic Epithelial Tumors for the Forthcoming 9th Edition of the TNM Classification of Malignant Tumors.
发表日期:2023 Sep 07
作者:
Edith M Marom, Wentao Fang, Enrico Ruffini, Frank Detterbeck, Usman Ahmad, Sarit Appel, Andrea Bille, Souheil Boubia, Cecilia Brambilla, Vanessa Cilento, Ayten Kayi Cangir, Conrad Falkson, Pier Luigi Filosso, Giuseppe Giaccone, Nicolas Girard, Emily Goren, Francesco Guerrera, James Huang, Maurizio Infante, Dong Kwan Kim, Marco Lucchi, Mirella Marino, Andrew G Nicholson, Meinoshin Okumura, Ramon Rami-Porta, Andreas Rimner, Charles B Simone, Hisao Asamura,
来源:
HEART & LUNG
摘要:
淋巴结图谱是准确确定和记录淋巴结分类的支柱。国际胸腺恶性肿瘤兴趣小组与肿瘤、淋巴结和转移(TNM)分类第八版合作,创建了第一个胸腺上皮恶性肿瘤地图,代表了胸腺上皮恶性肿瘤的第一个官方TNM分类。该图谱基于临床经验和已发表的研究,但由于数据有限,主要是经验性的。2017年的图谱传播和在全球范围内实施了标准胸腺分期分类,提供了更一致和细致的数据。与第八版数据库相比,当前数据库中的淋巴结受累病例数量多出两倍以上,这使得可以验证第八版图谱的许多方面。本文详细介绍了国际肺癌研究学会肺腺瘤分期和预后因素委员会胸腺领域的第九版TNM用于细化胸腺图谱的过程和考虑因素。委员会评估了一个大型国际合作数据库、有关胸腺上皮肿瘤淋巴结转移的已发表解剖和临床研究,以及作为第九版TNM分类细化基础的分析结果。根据保持第九版TNM分类的N组分不变的建议,淋巴结图谱也保持不变。但是,已添加澄清内容以促进临床使用。© 2023 Elsevier Inc. 发布
A lymph node map is the pillar on which accurate assignment and documentation of nodal classification stands. The International Thymic Malignancy Interest Group created the first map for thymic epithelial malignancies in conjunction with the 8th edition of the tumor, node and metastasis (TNM) classification, representing the first official TNM classification of thymic epithelial malignancies. The map was based on clinical experience and published studies, but was largely empiric because of limited available data. Dissemination of the map and implementation of a standard thymic stage classification across the world in 2017 has provided more consistent and granular data.More than twice as many cases of node involvement are available for analysis in the current database compared to that of the 8th edition database, allowing validation of many aspects of the 8th edition map. This article details the process and considerations for refinement of the thymic map for the 9th TNM used by the Thymic Domain of the Staging and Prognostic Factors Committee of the International Association for the Study of Lung Cancer. The committee evaluated a large international collaborative dataset, published anatomical and clinical studies pertaining to lymph node spread from thymic epithelial tumors, in conjunction with the analysis underlying refinements of the TNM components for the 9th edition TNM classification.Based on the recommendation to keep the N component unchanged for the 9th edition TNM classification, the lymph node map remains unchanged as well; however, clarifications have been added to facilitate clinical use.Copyright © 2023. Published by Elsevier Inc.