研究动态
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肿瘤切除手术、麻醉镇痛技术与肿瘤治疗效果:一篇叙述性综述。

Tumour excisional surgery, anaesthetic-analgesic techniques, and oncologic outcomes: a narrative review.

发表日期:2023 Sep 07
作者: Orla Murphy, Patrice Forget, Daqing Ma, Donal J Buggy
来源: BRITISH JOURNAL OF ANAESTHESIA

摘要:

癌症是一个不断增长的全球负担;据估计,2020年全球新增癌症诊断约为1800万例。切除手术仍然是癌症患者实体器官肿瘤的主要治疗方法,具有潜在的治愈效果。癌症和手术引起的炎症过程可能有助于残留肿瘤细胞的存活、生长和随后的复发。然而,有人提出了这样的假设,即手术期间的麻醉和镇痛技术可能会影响癌症复发的风险。本叙述性综述旨在提供关于特定麻醉和镇痛技术或手术围手术期干预措施是否对有治愈目的的肿瘤切除手术的长期肿瘤学结果产生实质影响的最新观察性研究和新的随机对照临床试验的综合总结。 版权所有 © 2023 作者。由Elsevier Ltd.出版。保留所有权利。
Cancer is a growing global burden; there were an estimated 18 million new cancer diagnoses worldwide in 2020. Excisional surgery remains one of the main treatments for solid organ tumours in cancer patients and is potentially curative. Cancer- and surgery-induced inflammatory processes can facilitate residual tumour cell survival, growth, and subsequent recurrence. However, it has been hypothesised that anaesthetic and analgesic techniques during surgery might influence the risk of cancer recurrence. This narrative review aims to provide an updated summary of recent observational studies and new randomised controlled clinical trials on whether certain specific anaesthetic and analgesic techniques or perioperative interventions during tumour resection surgery of curative intent materially affect long-term oncologic outcomes.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.