鉴于灵芝已被公认具有治疗特性，作为一种化学预防剂和功能性食品，它是广泛研究的蘑菇之一。它是一种已知的木质降解类担子菌，具有众多药理学功能，被称为天然药库，因其含有丰富的活性化合物，已被证明具有多种治疗性质。本综述重点研究了灵芝提取物在食品产品（如乳制品、酒类、饮料、烘焙食品、肉类及其他产品）的感官和营养特性上的潜力作为功能性成分。此外，该研究还探讨了包埋灵芝提取物的各个方面，包括形态学和流变学特性、益生元和免疫调节重要性、对凋亡、自噬、癌症治疗、炎症反应、氧化应激、抗氧化活性和安全性问题的影响。这些发现对食品和制药行业的新产品开发具有重要意义。另一方面，从灵芝中提取的各种活性化合物没有显示出毒性或副作用，对其作为膳食食品、天然疗法和强化健康食品的吸引力正在大幅增加，同时也吸引着工业界和科学界的兴趣。此外，基于灵芝的功能性食品的形成似乎在营养学、食品学和制药学领域具有实际前景和激动人心的前景。版权所有 © 2023 Elsevier Ltd. 保留所有权利。

Owing to the recognized therapeutic characteristics of G. lucidum, it is one of the most extensively researched mushrooms as a chemopreventive agent and as a functional food. It is a known wood-degrading basidiomycete possessing numerous pharmacological functions and is termed a natural pharmacy store due to its rich number of active compounds which have proved to portray numerous therapeutic properties. This current review highlights studies on the potentialities of G. lucidum extracts as functional ingredients on organoleptic and nutritional properties of food products (e.g., dairy, wine, beverage, bakery, meat, and other products). In addition, the study delved into various aspects of encapsulated G. lucidum extracts, their morphological and rheological characteristics, prebiotic and immunomodulatory importance, the effects on apoptosis, autophagy, cancer therapy, inflammatory responses, oxidative stress, antioxidant activities, and safety concerns. These findings have significant implications for the development of new products in the food and pharmaceutical industries. On the other hand, the various active compounds extracted from G. lucidum exhibited no toxic or adverse effects, and the appeal for it as a dietary food, natural remedy, and health-fortifying food is drastically increasing as well as attracting the interest of both the industrial and scientific communities. Furthermore, the formation of functional foods based on G. lucidum appears to have actual promise and exciting prospects in nutrition, food, and pharmaceutical sciences.Copyright © 2023 Elsevier Ltd. All rights reserved.