宫颈癌是全球妇女第二大癌症死因。鉴定有效的基因及其作为靶向剂的生物学标志物对于该病的诊断和治疗非常必要。生物信息学技术及遗传和分子研究为研究基因组、转录组、蛋白质组和代谢组等不同层次的信息提供了深度和准确性。这些数据的收集为包括癌症在内的各种复杂表型提供了全面且有价值的信息。本研究检测了与宫颈癌相关的三个基因LRP11、FUBP1和TET1。研究结果显示，这些基因在淋巴结和甲状腺中的表达水平较高，在胰腺和肝脏中较低。另外，FUBP1基因的表达水平高于LRP11基因，而LRP11基因的表达水平高于TET1基因。通过对所研究基因的结构和蛋白质组学的分析，可以看出由于LRP11和FUBP1基因中存在更多的结构域，这些基因可能独立参与不同的功能并具有比TET1基因更广泛的活动范围。另外，所检测基因的稳定性分析显示，FUBP1基因的稳定性相对较高，比TET1基因更稳定，同时该基因也比LRP11基因更稳定。考虑到这些基因是宫颈癌早期检测的关键基因，希望它们能够作为诊断和治疗宫颈癌的标志物。

Cervical cancer is the second leading cause of cancer death among women worldwide. Identification of effective genes along with biological markers as targeting agents is very necessary for the diagnosis and treatment of this disease. Bioinformatics techniques along with genetic and molecular investigations have provided the possibility of studying different levels of information such as the genome, transcriptome, proteome, and metabolize with high depth and accuracy. The collection of these data provides comprehensive and valuable information about the investigated phenotypes, including complex diseases such as cancer. In this study, we examined three genes LRP11, FUBP1, and TET1 related to cervical cancer. The results of this study showed that the level of expression of these genes is high in lymph nodes and the thyroid and is less in the pancreas and liver. Also, the expression level of the FUBP1 gene is higher than that of LRP11, and the expression level of the LRP11 gene is higher than that of TET1. Regarding the structure and proteomics of the studied genes, it can be seen that due to the presence of more domains in the LRP11 and FUBP1 genes, these genes probably independently participate in various functions and have a wider range of activity than the TET1 gene. Also, the analysis of the stability of the examined genes showed that the stability of the FUBP1 gene is relatively higher than that of the TET1 gene, and this gene is also more stable than the LRP11 gene. Considering that these genes are effective key genes for the early detection of cervical cancer, it is hoped that they will be used as markers in the diagnosis and treatment of cervical cancer.