2021年世界卫生组织关于胶质瘤分类以及对影像诊断的启示：第三部分-神经胶质瘤和神经元瘤的影像学发现总结。
The 2021 WHO Classification for Gliomas and Implications on Imaging Diagnosis: Part 3-Summary of Imaging Findings on Glioneuronal and Neuronal Tumors.
发表日期：2023 Sep 16
作者：
Yae Won Park, Philipp Vollmuth, Martha Foltyn-Dumitru, Felix Sahm, Kyu Sung Choi, Ji Eun Park, Sung Soo Ahn, Jong Hee Chang, Se Hoon Kim
来源：
MOLECULAR & CELLULAR PROTEOMICS
摘要：
2021年世界卫生组织中枢神经系统肿瘤分类第五版反映了传统基于组织病理学和最新分子诊断技术之间的过渡状态。本文的第三部分综述聚焦于胶质神经元和神经元肿瘤的分子诊断和影像学发现。胶质神经元和神经元肿瘤的组织学和分子特征常常与儿童型弥漫性低级别胶质瘤和周围性星形胶质瘤（在第二部分综述中讨论）有重叠之处。由于这种重叠，对于一些胶质神经元和神经元肿瘤的类型来说，组织病理学和遗传变异可能无法做出确切诊断，此时影像学特征可能有助于区分困难病例。因此，放射科医师理解潜在的分子诊断和影像学发现，并应用于临床实践非常重要。证据级别: 3，技术效力: 三级。© 2023 作者。由Wiley Periodicals LLC代表国际磁共振医学学会发表的《磁共振成像杂志》。
The fifth edition of the World Health Organization classification of central nervous system tumors published in 2021 reflects the current transitional state between traditional classification system based on histopathology and the state-of-the-art molecular diagnostics. This Part 3 Review focuses on the molecular diagnostics and imaging findings of glioneuronal and neuronal tumors. Histological and molecular features in glioneuronal and neuronal tumors often overlap with pediatric-type diffuse low-grade gliomas and circumscribed astrocytic gliomas (discussed in the Part 2 Review). Due to this overlap, in several tumor types of glioneuronal and neuronal tumors the diagnosis may be inconclusive with histopathology and genetic alterations, and imaging features may be helpful to distinguish difficult cases. Thus, it is crucial for radiologists to understand the underlying molecular diagnostics as well as imaging findings for application on clinical practice. EVIDENCE LEVEL: 3 TECHNICAL EFFICACY: Stage 3.© 2023 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.