女性尿道原发黑素瘤：一例在瓦加杜古诊断的病例。
[Primary melanoma of female urethra: A case diagnosed in Ouagadougou].
发表日期：2023 Sep 14
作者：
Aimé Sosthène Ouedraogo, Franck Auguste Hermann Adémayali Ido, Ibrahim Savadogo, Souleymane Ouattara, Rakiswendé Alexis Ouedraogo, Aïda Sandrine Ouedraogo, Assita Sanou-Lamien, Olga M Lompo
来源：
Cellular & Molecular Immunology
摘要：
我们报告了一例48岁女性尿道原发黑色素瘤的病例，该病例处于非转移期，患者有乳腺癌病史，曾接受放疗和激素治疗。患者就诊原因是排尿困难、血尿和会阴疼痛。临床检查发现尿道前上部为主的外阴鼓出并出现黑色肿块。肿块活检结果显示，肿瘤细胞呈梭形和球形，富含黑色素，并表达抗HMB 45和PS 100抗体。扩展评估显示没有出现继发定位。患者接受了全膀胱尿道切除术，未进行腹股沟淋巴结清扫。手术后100天未观察到复发情况。版权所有 © 2023. Elsevier Masson SAS出版。
We report a case of primary melanoma of a female urethra diagnosed at a non-metastatic stage in a 48-year-old patient with a history of breast carcinoma treated with radiotherapy and hormone therapy. The patient was consulting for dysuria, hematuria, and perineal pain. The clinical examination found a prolapsed and black mass, developed at the expense of the urethra and located at the anterosuperior part of the vulva. The mass biopsy revealed a proliferation of fusiform and globular cells loaded with black pigment expressing the anti-HMB 45 and PS 100 antibodies. The extension assessment showed an absence of secondary localization. The patient underwent total cystourethrectomy without inguinal lymphadenectomy. There was no recurrence observed on day 100 following the surgery.Copyright © 2023. Published by Elsevier Masson SAS.