磁共振成像（MRI）用于子宫颈癌的预治疗分期。本研究中，我们使用预治疗图像将手术病例分为两组，并评估其预后。本研究纳入了53例患有鳞状细胞癌并接受根治性子宫切除术的子宫颈癌患者。根据MRI结果，将患者分为清晰和不清晰肿瘤边界两组。评估每个患者的以下特征：总生存期、无复发生存期、淋巴结转移、淋巴管内浸润和病理结果，包括维门蛋白的免疫组化分析。清晰肿瘤边界组包括40例患者，不清晰肿瘤边界组包括13例患者。与清晰肿瘤边界组相比，不清晰肿瘤边界组的复发率更高（分别为3/40 vs. 3/13）、淋巴管内浸润率更高（分别为24/40 vs. 13/13）、淋巴结转移率更高（分别为6/40 vs. 10/13），以及维门蛋白阳性率更高（分别为18/40 vs. 10/13）。尽管复发无病生存期没有显著差异（p = 0.0847），不清晰肿瘤边界组的整体生存期明显较清晰肿瘤边界组差（p = 0.0062）。根据MRI结果，鳞状细胞子宫颈癌患者的不清晰肿瘤边界与预后较差、淋巴结转移和远处转移复发有关。© 2023年。Springer Nature Limited.

Magnetic resonance imaging (MRI) is used for pretreatment staging in cervical cancer. In the present study, we used pretreatment images to categorize operative cases into two groups and evaluated their prognosis. A total of 53 cervical cancer patients with squamous cell carcinoma who underwent radical hysterectomy were included in this study. Based on MRI, the patients were classified into two groups, namely clear and unclear tumor border. For each patient, the following characteristics were evaluated: overall survival; recurrence-free survival; lymph node metastasis; lymphovascular space invasion; and pathological findings, including immunohistochemical analysis of vimentin. The clear and unclear tumor border groups included 40 and 13 patients, respectively. Compared with the clear tumor border group, the unclear tumor border group was associated with higher incidence rates of recurrence (3/40 vs. 3/13, respectively), lymphovascular space invasion (24/40 vs. 13/13, respectively), lymph node metastasis (6/40 vs. 10/13, respectively), and positivity for vimentin (18/40 vs. 10/13, respectively). Despite the absence of significant difference in recurrence-free survival (p = 0.0847), the unclear tumor border group had a significantly poorer overall survival versus the clear tumor border group (p = 0.0062). According to MRI findings, an unclear tumor border in patients with squamous cell cervical cancer is linked to poorer prognosis, lymph node metastasis, and distant recurrence of metastasis.© 2023. Springer Nature Limited.