人参皂苷对皮肤疾病的作用 - 一项系统综述
Effect of anti-skin disorders of ginsenosides- A Systematic Review.
发表日期：2023 Sep
作者：
Lele Cong, Jinli Ma, Yundong Zhang, Yifa Zhou, Xianling Cong, Miao Hao
来源：
ANTIOXIDANTS & REDOX SIGNALING
摘要：
人参皂苷是泛科的生物活性成分，具有抗衰老、抗氧化、抗炎、抗疲劳和抗肿瘤等多种功能。根据其无酚基结构，将人参皂苷分为三类三环萜烯类：腈烷型、齐看烷型和赖煤蒽型。根据连接到C-3、C-20和C-6、C-20的糖基单元，腈烷型又细分为原人参二醇（PPD）和原人参三醇（PPT）。人参皂苷对皮肤疾病的影响值得关注。通过增强免疫功能、抑制黑色素形成、抑制氧化作用以及提高胶原蛋白和透明质酸的浓度，它们发挥抗衰老作用。因此，人参皂苷以前被广泛应用于抵抗皮肤疾病和衰老。本综述从机制和实验研究的角度详细介绍了人参皂苷在抗皮肤衰老过程中的作用。© 2023 高世期出版服务由Elsevier B.V提供。
Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play anti-aging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.© 2023 The Korean Society of Ginseng. Publishing services by Elsevier B.V.