我们通过使用1988年至2017年的癌症死亡数据，对年失去生活年数（YLL）在常规癌症统计学中的应用进行了研究。英国癌症登记协会提供了1988年至2017年的英国17种癌症和全部癌症的死亡数据，按性别、5年年龄组和年份进行了分类。估计了YLL、年龄标化YLL率（ASYR）和年龄标化死亡率（ASMR）。在时期为1988年至1992年和2013年至2017年的时间段内，每年因癌症导致的平均YLL约为220万年和230万年，相应的年龄标化YLL率为4510和3823每10万年。在2013-2017年期间，肺癌、结肠癌和乳腺癌的YLL数量最多。所有癌症的年龄组YLL显示在60-64岁和75-79岁之间达到峰值。各种癌症在发病率、死亡率和YLL方面的相对贡献是不同的。例如，胰腺癌（在男性和女性中）在发病率中所占比例较小（3%），但在死亡率（6%和5%）和YLL（5%和6%）中所占比例较大，而前列腺癌（占发病率的26%）贡献了13%的死亡率和9%的YLL。YLL是衡量不同癌症对社会影响的有用指标，并对年轻人的癌症死亡给予了更高的权重。© 2023. The Author(s).

We investigated the application of years of life lost (YLL) in routine cancer statistics using cancer mortality data from 1988 to 2017.Cancer mortality data for 17 cancers and all cancers in the UK from 1988 to 2017 were provided by the UK Association of Cancer Registries by sex, 5-year age group, and year. YLL, age-standardised YLL rate (ASYR) and age-standardised mortality rate (ASMR) were estimated.The annual average YLL due to cancer, in the time periods 1988-1992 and 2013-2017, were about 2.2 and 2.3 million years, corresponding to 4510 and 3823 ASYR per 100,000 years, respectively. During 2013-2017, the largest number of YLL occurred in lung, bowel and breast cancer. YLL by age groups for all cancers showed a peak between 60-64 and 75-79. The relative contributions to incidence, mortality, and YLL differ between cancers. For instance, pancreas (in women and men) made up a smaller proportion of incidence (3%) but bigger proportion of mortality (6 and 5%) and YLL (5 and 6%), whereas prostate cancer (26% of incidence) contributed 13% mortality and 9% YLL.YLL is a useful measure of the impact different cancers have on society and puts a higher weight on cancer deaths in younger individuals.© 2023. The Author(s).