脉络丛肿瘤（CPT）是相对罕见的中枢神经系统肿瘤，主要发生在儿童中。根据组织学特征，它们被分为低级别脉络丛乳头状瘤（包括非典型的）和高级别脉络丛癌。对于这些复杂肿瘤已进行了广泛的学术研究。本研究的目标是鉴别与CPT相关的引用最多的100篇文章，以更好地了解迄今为止最具影响力的研究。2023年8月，使用爱思唯尔的Scopus数据库搜索了有关CPT的100篇引用最多的文章。为了寻找趋势，文章被分类为基础科学或临床，最早的50篇文章与最新的50篇文章进行了比较。使用Pearson's卡方精确检验和Wilcoxon秩和检验/Mann-Whitney U检验对各种文献计量参数进行了总结和比较。这100篇最常被引用的文章发表于1955年至2016年间的53种不同科学期刊，来自16个不同国家。超过75％的文章具有临床性质，总体平均值（范围）如下：引用次数78.5（42-371），年平均引用率3.4（0.9-12），作者数量6.2（1-28）。与较旧的文章相比，较新的文章在引用率（P<0.01）和作者数量（P<0.01）方面具有统计学上更高的差异。此外，虽然文章的焦点没有显著差异（P=0.64），但研究设计方面存在差异（P<0.01）。本研究使用引用数量作为文章影响力的替代指标，并鉴别了100篇最常被引用的CPT文章。新的突变分析为进一步亚组分组提供了可能，积极的合作趋势为改善治疗效果和长期生存带来了希望。© 2023年作者，授予Springer-Verlag GmbH德国独家许可，属于Springer Nature的一部分。

Choroid plexus tumors (CPT) are relatively rare CNS tumors that primarily occur in children. They are classified as low-grade choroid plexus papilloma, including atypical ones, and high-grade choroid plexus carcinoma based on histological characteristics. There has been extensive academic research regarding these complex tumors. The goal of this work was to identify the 100 most-cited articles pertaining to CPTs in order to better understand the most impactful studies to date.In August 2023, Elsevier's Scopus database was searched for the 100 most-cited articles about CPT. To look for trends, articles were classified as either basic science or clinical, and the earliest 50 articles were separated from the latest 50 articles and then were compared. Various bibliometric parameters were summarized and compared using Pearson's chi-square exact test and Wilcoxon rank sum test/Mann-Whitney U test.The 100 most-cited articles were published between 1955 and 2016 in 53 different scientific journals, originating from 16 distinct countries. Over 75% of the articles were clinical in nature, and overall mean (range) values were as follows: citation count 78.5 (42-371), citation rate per year 3.4 (0.9-12), number of authors 6.2 (1-28). Newer articles had statistically higher citation rate (P < 0.01) and number of authors (P < 0.01) compared to their older counterparts. Additionally, while there was no significant difference in article focus (P = 0.64), there was a difference in study design (P < 0.01).This study used citation number as a surrogate for article impact and identified the 100 most-cited CPT articles. New mutational analyses have allowed for further subgrouping and positive trends in collaboration shine hope for improvement in treatment outcomes and long-term survival.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.