肾细胞癌（RCC）是泌尿系统中第三常见的恶性肿瘤。肺部、骨骼、淋巴结、肝脏和脑部都是RCC常见的转移部位。然而，关于RCC单独网膜转移的文献有限。我们报道了一例44岁男性患者，在腹腔镜下行根治性肾切除术后出现RCC单个网膜转移的病例。切除的左肾病理诊断为pT3a清细胞RCC（Fuhrman分级III）。术后6个月，腹部计算机断层扫描显示左下腹膜出现一个12mm的增强结节。术后7个月，行腹腔镜切除左网膜结节，病理结果显示转移的清细胞RCC。目前患者正在接受辅助性的pembrolizumab治疗。由于腹腔镜下根治性肾切除术引起的RCC网膜转移较为罕见，泌尿科医生应意识到RCC的多样性特点。© 作者2023年. 由白世登出版集团发表。保留所有权利。

Renal cell carcinoma (RCC) is the third most common malignancy in the genitourinary tract. The lungs, bone, lymph nodes, liver, and brain are common metastatic sites of RCC. However, there is limited literature on single omental metastasis of RCC.We present the case of a 44-year-old man with single omental metastasis of RCC after laparoscopic radical nephrectomy. Pathological diagnosis of the resected left kidney revealed pT3a clear cell RCC (Fuhrman grade III). At 6 mo postoperatively, abdominal computed tomography revealed a 12-mm enhancing nodule in the left lower peritoneum. At 7 mo after initial operation, laparoscopic removal of the left omental nodule was performed. The pathological results indicated metastatic clear cell RCC. Currently, the patient is being treated with adjuvant pembrolizumab.Omental metastasis of RCC owing to laparoscopic radical nephrectomy is rare. Urologists should be aware of the diverse nature of RCC.©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.