癌症是全球第二大死因。近年来，其发病率不断增加，已成为人类健康的重大威胁。传统的癌症治疗策略，包括手术、化疗和放疗，面临药物耐药、毒副作用和治疗效果不佳等问题。因此，更好地开发和利用生物材料可以提高肿瘤治疗的特异性和疗效。藻类作为一种新型的生物材料，具有良好的生物相容性。虽然一些综述已经阐明了几种基于藻类的抗癌生物材料，但绝大部分文献仅关注少数几种藻类。因此，当前缺乏关于抗癌藻类的综合综述。本综述旨在通过对具有潜在抗癌活性的藻类物种进行彻底检查，填补这一空白。此外，我们的综述还将阐明藻类的工程策略，并讨论与其应用相关的挑战和前景。©2023年 Xin等。

Cancer is the second leading cause of death worldwide. Its incidence has been increasing in recent years, and it is becoming a major threat to human health. Conventional cancer treatment strategies, including surgery, chemotherapy, and radiotherapy, have faced problems such as drug resistance, toxic side effects and unsatisfactory therapeutic efficacy. Therefore, better development and utilization of biomaterials can improve the specificity and efficacy of tumor therapy. Algae, as a novel living material, possesses good biocompatibility. Although some reviews have elucidated several algae-based biomaterials for cancer treatment, the majority of the literature has focused on a limited number of algae. As a result, there is currently a lack of comprehensive reviews on the subject of anticancer algae. This review aims to address this gap by conducting a thorough examination of algal species that show potential for anticancer activity. Furthermore, our review will also elucidate the engineering strategies of algae and discuss the challenges and prospects associated with their implementation.© 2023 Xin et al.