本研究旨在评估膀胱癌（BC）患者慢性阻塞性肺疾病（COPD）死亡风险。从Surveillance, Epidemiology, and End Results（SEER）数据库中收集了2000年至2016年间确诊为BC的患者的病理学数据。根据一般人群的参考数据，计算出标准化死亡率（SMR）。使用Nelson-Aalen累积危险曲线评估BC患者COPD死亡风险。进行了多变量竞争风险模型。使用Schoenfeld残差对比例风险假设进行测试，对于每个风险因素，将其按时间缩放并绘制。从SEER数据库中确定了共有237,563名BC患者进行进一步分析，其中5,198名患者经历了COPD死亡；BC患者COPD死亡的总体SMR为1.58（95% CI：1.54-1.63）。年龄、种族、诊断年份、组织学类型、总结分期、手术、婚姻状况、大学教育水平和家庭收入中位数独立预测了BC患者的COPD死亡。与一般人群相比，BC患者的COPD死亡风险显著增高。预先确认高危人群和提供呼吸护理措施是有效改善该患者群体存活的重要措施。

This study was designed to evaluate risk of mortality from chronic obstructive pulmonary disease (COPD) in patients with bladder cancer (BC).Data on patients diagnosed with BC by pathology between 2000 and 2016 were collected from the Surveillance, Epidemiology, and End Results (SEER) database. Based on reference data from the general population, the standardized mortality rate (SMR) is calculated. Nelson-Aalen cumulative hazard curves were used for assessment of the risk of COPD mortality in BC patients. Multivariable competing risk models were conducted. The proportional hazards assumption was tested using Schoenfeld residuals, which were scaled and plotted over time for each risk factor.A total of 237,563 BC patients were identified for further analysis from the SEER database, 5,198 of these patients experienced COPD mortality; the overall SMR for COPD mortality in BC patients was 1.58 (95% CI: 1.54-1.63). Age, race, year of diagnosis, histologic type, summary stage, surgery, marital status, college education level, and median household income independently predicted COPD mortality in BC patients.In comparison to the general population, the risk of COPD mortality is significantly higher in patients with BC. Pre-identification of high-risk groups and respiratory care provisions are important measures to effectively improve survival in this group of patients.