评估和相关性研究成年患者在COVID-19大流行期间接受造血干细胞移植的生活质量和财务毒性。在拉丁美洲的一家移植参考医院进行了一项35名患者的观察性分析研究。使用肿瘤功能评估骨髓移植问卷和财务毒性综合评分问卷进行数据收集。采用Spearman和Mann-Whitney相关性检验进行数据分析。COVID-19期间的一般生活质量得分较低（67.09/108），其功能福祉（14.47/28），社会福祉（16.76/28）和额外关注事项（23.41/40）更为受损。在所有领域中，异基因组的平均值低于自体组，与额外关注事项（p=0.01）和治疗评估指数（p=0.04）的相关性存在显著差异。财务毒性被认为对生活质量产生轻微影响（22.11/44）。生活质量与财务毒性之间存在关系，尽管不显著（p=0.051）。样本的生活质量较低；生活质量和财务毒性存在相关性，尽管不显著。财务毒性越高，生活质量越低。

to evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic.observational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis.general quality of life during COVID-19 had a low score (67.09/108) with greater impairment in functional well-being (14.47/28), social well-being (16.76/28) and additional concerns (23.41/40). The means of the allogeneic group were lower than those of the autologous group in all domains, showing a significant difference in relation to additional concerns (p=0.01) and in the treatment evaluation index (p=0.04). Financial toxicity was considered to have a slight impact (22.11/44). There was a relationship, albeit not significant, between quality of life and financial toxicity (p=0.051).the quality of life of the sample was low; there is a correlation between quality of life and financial toxicity, although not significant. The higher the financial toxicity, the lower the quality of life.