研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

萨木迪尔多伐大黄的植物化学和现代药理学的进展

Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata (Turcz.) Schischk.

发表日期:2023 Sep 21
作者: Jun-Wen Gao, Yang Zhan, Yun-He Wang, Shu-Jie Zhao, Zhong-Ming Han
来源: ANTIOXIDANTS & REDOX SIGNALING

摘要:

分枝芹(学名:Saposhnikovia divaricata (Turcz.) Schischk,简称:分枝芹,拼音:fēnzhī qín)是伞形科的一种草本植物,其根自西汉时代(公元前202年)起被应用。分枝芹中的药理活性物质主要为染料苷和香豆素。现代植物化学和药理学研究已证明其具有退热、镇痛、抗炎、抗氧化、抗肿瘤和抗凝血活性。技术和分析策略理论的进展取得了新的成果,但绝大多数研究仅限于主要药理活性物质染料苷和香豆素的部分。因此,我们回顾了与分枝芹的化学成分和药理活性相关的研究,分析了发展趋势和面临的挑战,并提出研究应重点关注成分的协同效应。我们还建议在进一步研究中优先考虑结构-效应关系。© 2023 中国中西医结合杂志社和Springer-Verlag GmbH Germany,Springer Nature旗下公司。
Saposhnikovia divaricata (Turcz.) Schischk (S. divaricata, Fangfeng) is a herb in the Apiaceae family, and its root has been used since the Western Han Dynasty (202 B.C.). Chromones and coumarins are the pharmacologically active substances in S. divaricata. Modern phytochemical and pharmacological studies have demonstrated their antipyretic, analgesic, anti-inflammatory, antioxidant, anti-tumor, and anticoagulant activities. Technological and analytical strategy theory advancements have yielded novel results; however, most investigations have been limited to the main active substances-chromones and coumarins. Hence, we reviewed studies related to the chemical composition and pharmacological activity of S. divaricata, analyzed the developing trends and challenges, and proposed that research should focus on components' synergistic effects. We also suggested that, the structure-effect relationship should be prioritized in advanced research.© 2023. The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature.