为了研究两种类型的温度冲洗对经皮内窥镜椎间盘切除术中体温、炎症细胞因子水平和出血量的影响，我们选择了2018年1月至2020年12月进行经皮内窥镜椎间盘切除术的80名患者，并将其分为实验组（40例）和对照组（40例）。实验组中有19名男性和21名女性，年龄为（38.8±9.8）岁；L4,5椎间盘切除7例，L5S1椎间盘切除33例；体重指数（BMI）为（27.8±7.2）kg·m-2。对照组中有18名男性和22名女性，年龄为（41.5±10.9）岁；L4,5椎间盘切除5例，L5S1椎间盘切除35例；BMI为（26.4±6.2）kg·m-2。对照组患者在室温下接受生理盐水冲洗，实验组患者接受37℃加热的生理盐水冲洗。记录体温、发冷、恶心、呕吐和其他不良反应。记录两组在手术前和术后2小时的肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）和白细胞介素-10（IL-10）水平。术前和术后2小时使用视觉模拟评分（VAS）评估两组的腰痛程度。记录术前和术后2小时的纤溶-凝血指标，包括D-二聚体（DD）、纤维蛋白原降解产物（FDP）、活化部分凝血酶时间（APTT）和凝血酶时间（PT）。记录两组的手术时间和出血量。两组的体温呈下降趋势，但对照组的体温低于实验组。两组术后2小时与术前相比，TNF-α、IL-6和IL-10的水平都有增加（P<0.05），但实验组的水平低于对照组（P<0.05）。实验组的术后VAS评分为2.19±1.13，明显低于对照组的3.38±1.35（P<0.05）。两组在术后2小时的DD和FDP水平均高于术前水平（P<0.05），但实验组的水平高于对照组（P<0.05）。两组在术后的APTT和PT水平之间没有显著差异（P>0.05）。实验组的术中出血量（45.2±14.1）ml低于对照组的（59.52±15.6）ml。实验组的手术时间（46.7±13.8）分钟少于对照组的（58.3±15.2）分钟（P<0.05）。体温冲洗可以减少不良反应的发生率，减轻局部炎症反应，减少术中出血量并缩短手术时间。

To investigate the effects of two types of temperature rinses on body temperature, inflammatory cytokine levels, and bleeding volume in percutaneous endoscopic lumbar discectomy.Eighty patients underwent percutaneous endoscopic lumbar discectomy from January 2018 to December 2020 were selected and divided into experimental group (40 cases) and control group(40 cases). In experimental group, there were 19 males and 21 females, aged (38.8±9.8) years old;7patients on L4,5 and 33 patients on L5S1;Body msss index(BMI) was (27.8±7.2) kg·m-2. In contral group, there were 18 males and 22 females, aged (41.5±10.9) years old, 5 patients on L4,5 and 35 patients on L5S1;BMI was (26.4±6.2) kg·m-2. The patients in the control group were received normal saline rinse at room temperature, and the patients in the experimental group were received normal saline rinse heated to 37 ℃. Body temperature, chills, nausea, vomiting, and other adverse reactions were recorded. The levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-10 (IL-10) in two groups were recorded before and 2 hours after operation. Visual analogue scale (VAS) was used to evaluate the degree of lumbar pain in two groups before and 2 hours after surgery. Fibrinolytic-coagulation indexes with preoperative and 2 hours after surgery, including the D-dimer (DD), fibrinogen degradation products (FDP), activated partial thrombin time (APTT) and prothrombin time (PT) were recorder. Operation time and blood loss in two groups were recorded.The body temperature of both groups showed a downward trend, while the body temperature of the control group was lower than that of the experimental group. The levels of TNF-α, IL-6 and IL-10 in two groups were increased 2 hours after surgery compared with those before surgery(P<0.05), while the levels in experimental group were lower than those in control group(P<0.05). Postoperative VAS in experimental group 2.19±1.13 was significantly lower than that in the control group 3.38±1.35(P<0.05). The levels of DD and FDP at 2 hours after surgery in both groups were higher than those before surgery (P<0.05), while the levels of DD and FDP in the experimental group were higher than those in the control group (P<0.05). There was no significant difference in APTT and PT levels between two groups after operation (P>0.05). The blood loss in the experimental group of (45.2±14.1) ml was lower than that in the control group of (59.52±15.6) ml. The operation time of experimental group (46.7±13.8) min was less than that of control group (58.3±15.2) min(P<0.05).Body temperature rinse can reduce the incidence of adverse reactions, alleviate local inflammatory reactions, reduce intraoperative blood loss and shorten the operation time.