研究动态
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在切层皮肤移植供体部位迅速发展鳞状细胞癌。

Rapid development of squamous cell carcinoma at a split-thickness skin graft donor site.

发表日期:2023
作者: Andrew P Bain, Kareem R AbdelFattah, Audra T Clark
来源: Burns & Trauma

摘要:

在切取厚度为分离层皮肤移植供体部位发展麦尔金溃疡是非常罕见的。在这里,我们描述了在严重烧伤的情况下,在切取厚度为分离层皮肤移植供体部位快速发展鳞状细胞癌的情况。我们报告了一名52岁的男性病例,无既往病史,因火焰闪烁引起24%体表面积烧伤。在初始切除和移植手术后的四个月,他前来修复烧伤瘢痕,并抱怨供体部位有一个迅速发展的皮肤病变,此病变在两周内出现。该病变被全部切除,并证实为浸润性鳞状细胞癌。此前有5例在严重烧伤情况下切取厚度为分离层皮肤引起鳞状细胞癌的报道。虽然典型的麦尔金溃疡潜伏期可长达30年,但在切取厚度为分离层皮肤移植供体部位出现的病变似乎具有迅速发生的特点,通常为数周至数月。在切取厚度为分离层皮肤移植供体部位发展鳞状细胞癌是烧伤护理中罕见但重要的后遗症。IJBT 版权所有 © 2023。
The development of a Marjolin ulcer at the site of a split-thickness skin graft donor site is exceptionally rare. Here we describe the rapid development of squamous cell carcinoma at a split-thickness skin graft donor site in the setting of severe burn. We present a case of a 52-year-old male with no past medical history who presented with a 24% total body surface area burn caused by a flash flame. Four months after his initial excision and grafting, he presented for revision of a burn scar with an additional complaint of a rapidly developing skin lesion at his donor site, which arose over 2 weeks. The lesion was excised en bloc and found to be invasive squamous cell carcinoma. There are 5 previous cases of squamous cell carcinoma development at the site of split-thickness skin harvest in the setting of severe burn. While the typical Marjolin ulcer has a latency period of up to 30 years, lesions that arise in split-thickness skin graft donor sites appear to have a rapid onset of weeks to months. Squamous cell carcinoma at the site of split-thickness skin grafting is an uncommon but important sequelae of burn care.IJBT Copyright © 2023.